2026-06-05T17:55:47Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/194072026-02-03T11:56:00Zcom_10630_2254col_10630_37959
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Sampedro-Piquero, Patricia
author
Vicario, Selene
author
Pérez-Rivas, Aroa
author
Ladrón de Guevara-Miranda, David
author
Santín-Núñez, Luis Javier
2020-03-17T10:08:05Z
2020-03-17T10:08:05Z
2020-03-17
https://hdl.handle.net/10630/19407
Introduction: The concept of cognitive reserve (CR) is being considered in the field of substance use disorder (SUD) by observing that there are individuals whose brain alterations are not related to the cognitive symptomatology they present. Aims: Our aims were to characterise the possible neuropsychological deficits in a sample of subjects with SUD compared to a control group and to determine whether the degree of CR is a mediator in the cognitive functioning of these patients. Methods: To perform these objectives, the study involved a sample of subjects with SUD in outpatient treatment and a control group. A CR questionnaire and a comprehensive neuropsychological assessment were administered, and we also collected data related to drug consumption and psychological well-being. Results: The SUD group showed poorer performance compared to the control group in several cognitive domains (attention, declarative memory, executive functions and emotional perception), as well as in psychological comfort. Interestingly, we observed that the deficits found in attention, declarative memory and executive functions were mediated by the CR level of the participants, an effect that we did not observe in the rest of the variables registered. Conclusion: Our results suggest that long-term drug consumption leads to cognitive deficits and affects the psychological well-being of the subjects. Moreover, the CR should be taken into account during the assessment and rehabilitation of patients with SUD due to its protective role against certain neuropsychological deficits.
eng
Neurociencia cognitiva
Cognitive reserve mediates the severity of certain neuropsychological deficits related to cocaine use disorder
conference output
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URL
https://riuma.uma.es/bitstreams/90044ded-5494-4840-b6c6-d1a85259066f/download
File
MD5
3013f4f5fe8990f44ac745dfb8a434eb
183774
application/pdf
Abstract FANPSE 2020.pdf