2026-05-28T19:20:12Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/260372026-02-03T11:06:39Zcom_10630_2254col_10630_37953

00925njm 22002777a 4500 dc Espada-Sánchez, Marta author Saenz de Santa María-García, Rocío author Martín Astorga, María del Carmen author Lebrón-Martín, Clara author Romero-Delgado, María-Jesús author Eguiluz-Gracia, Ibón author Rondón Segovia, Carmen author Mayorga Mayorga, Cristobalina author Torres-Jaén, María Josefa author Aranda, Carlos José author Cañas, José Antonio author 2023-01-18 Respiratory diseases are pathological conditions that affect airways, hampering breathing and causing high mortality. In particular, asthma and allergic rhinitis (AR) are two of the most common airway diseases that affect millions of people and have a high prevalence in childhood and adulthood. Asthma is a heterogeneous chronic inflammatory disease characterized by wheezing, chest tightness, shortness of breath, and cough. AR occurs with rhinorrhea, nasal congestion, and sneezing. Indeed, these pathologies share common physiopathological mechanisms such as airway hyperresponsiveness and similar immunopathology such as tissue eosinophilia and T-helper type 2 inflammation. Moreover, AR can be an important risk factor for suffering asthma. Thus, early diagnosis and effective treatment are crucial to improving the health and quality of life of these patients. Classical drugs such as corticosteroids have been used; however, in the last decades, efforts to improve treatments have increased, focusing on biological agents and specific allergen immunotherapy development. Moreover, more precise diagnostic tools have been elaborated, besides classical methods (medical history, physical examination, and pulmonary function tests), such as basophil activation test, and specific cellular and molecular biomarkers (microRNAs, sputum/blood eosinophils, IgE serum, and periostin levels). Therefore, in this review, we compile all these important issues for managing asthma and AR. Espada-Sánchez M, Sáenz de Santa María R, Martín-Astorga MdC, Lebrón-Martín C, Delgado MJ, Eguiluz-Gracia I, Rondón C, Mayorga C, Torres MJ, Aranda CJ, Cañas JA. Diagnosis and Treatment in Asthma and Allergic Rhinitis: Past, Present, and Future. Applied Sciences. 2023; 13(3):1273. https://doi.org/10.3390/app13031273 https://hdl.handle.net/10630/26037 https://doi.org/10.3390/app13031273 Alergia Diagnosis and Treatment in Asthma and Allergic Rhinitis: Past, Present, and Future