2026-06-07T05:13:53Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/264612026-02-03T10:56:19Zcom_10630_2254col_10630_37953
Diagnosis of immediate reactions to amoxicillin: Comparison of basophil activation markers CD63 and CD203c in a prospective study
Céspedes Lagos, José Antonio
Fernández-Santamaría, Rubén
Ariza Veguillas, Adriana
Bogas Herrera, Gádor
Doña, Inmaculada
Rondón, Carmen
Salas, María
Labella, Marina
Frecha, Cecilia
Mayorga Mayorga, Cristobalina
Torres-Jaén, María Josefa
Fernández-Duarte, Tahía Diana
Agentes anticancerosos
Amoxicilina
Basófilos
Diágnosticos
Amoxicillin (AX) combined or not with clavulanic acid (CLV) is frequently involved in IgE-mediated reactions. Drug provocation test (DPT) is considered as the gold standard for diagnosis, although contraindicated in high-risk patients. Basophil activation test (BAT) can help diagnose immediate reactions to beta-lactams, although controversy exists regarding the best activation marker. We have performed a real-life study in a prospective cohort to analyze the real value of BAT as diagnostic tool and the best activation marker, CD63 and CD203c, for the evaluation of immediate reactions to these drugs.
2023-05-04T11:12:56Z
2023-05-04T11:12:56Z
2023-05-04T11:12:56Z
2022-12-07
journal article
Céspedes, J. A., Fernández‐Santamaría, R., Ariza, A., Bogas, G., Doña, I., Rondón, C., ... & Fernández, T. D. (2022). Diagnosis of immediate reactions to amoxicillin: Comparison of basophil activation markers CD63 and CD203c in a prospective study. Allergy.
https://hdl.handle.net/10630/26461
DOI: 10.1111/all.15610
eng
http://creativecommons.org/licenses/by-nc-nd/4.0/
open access
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Wiley