2026-05-31T09:12:19Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/271042026-02-03T11:16:51Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Martinez-Corral, Inés
author
Trevaskis, Natalie L.
author
García-Caballero, Melissa
2023-06-28T09:57:21Z
2023-06-28T09:57:21Z
2022-04-25
Martinez-Corral I, Trevaskis NL and García-Caballero M (2022) Editorial: Modulating Vascular Lymphatic Growth in Disease: Current and Potential Pharmacological Approaches for Prevention and Treatment. Front. Pharmacol. 13:910142. doi: 10.3389/fphar.2022.910142
https://hdl.handle.net/10630/27104
doi: 10.3389/fphar.2022.910142
The lymphatic system is part of the circulatory system and it is indispensable for life. In physiological conditions, the main functions assigned to the lymphatic system are the maintenance of the interstitial fluid homeostasis, immune surveillance and the absorption of dietary fat in the intestine (Alitalo, 2011). However, morphological or functional changes in lymphatic vessels can contribute to disorders such as lymphedema, tumor metastasis, inflammation and other pathological conditions (Oliver et al., 2020). Therefore, there is an urgent need to further understand the mechanisms driving lymphatic dysfunction in these conditions and to develop novel lymph-targeted therapies. In this Research Topic, we present a collection of research articles that provide new insights into obesity-induced lymphatic dysfunction and tumor-draining lymph node reconstruction; and review articles that highlight and discuss the latest pharmacological approaches to treat lymphedema and mechanisms to target obesity and metabolic diseases through modulating lymphatic contraction.
eng
Sistema linfático - Enfermedades
Modulating Vascular Lymphatic Growth in Disease: Current and Potential Pharmacological Approaches for Prevention and Treatment
journal article
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URL
https://riuma.uma.es/bitstreams/144c0613-9f38-49fb-b67d-2ae75e368097/download
File
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cf2143e58d4c0653387a04396a32598a
553095
application/pdf
fphar-13-910142.pdf