2026-05-30T07:51:27Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/277742026-02-03T11:30:40Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Salcedo Lobera, Esperanza
author
Arroyo Varela, Macarena
author
Larrosa-Jiménez, Rafael
author
Bautista-Moreno, Rocío
2023-10-09T09:49:55Z
2023-10-09T09:49:55Z
2023-08-29
Lobera, E.S., Varela, M.A., Jimenez, R.L. et al. miRNA as biomarker in lung cancer. Mol Biol Rep (2023). https://doi.org/10.1007/s11033-023-08695-9
https://hdl.handle.net/10630/27774
https://doi.org/10.1007/s11033-023-08695-9
Lung cancer has a high prevalence and mortality due to its late diagnosis and limited treatment, so it is essential to find biomarkers that allow a faster diagnosis and improve the survival of these patients. In this sense, biomarkers based on miRNAs have supposed a considerable advance. miRNAs, which are small RNA sequences, can regulate gene expression, so they play an essential role not only as a diagnostic biomarker but also as a therapeutic and prognostic one. Also, miRNA biomarkers can be obtained from liquid biopsies, which are less intrusive than lung biopsies, and have better accessibil-ity, safety and repeatability, which allows using those biomarkers both for diagnosis and monitoring of patients. In this review, we highlight the importance of miRNAs and collect the existing evidence of their relationship with lung cancer.
eng
Atribución 4.0 Internacional
Cáncer - Investigación
Pulmones - Cáncer - Diagnóntico - Innovaciones tecnológicas
miRNA as biomarker in lung cancer
journal article
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URL
https://riuma.uma.es/bitstreams/011c7cef-e265-4d6d-865f-9f9660d146cb/download
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781b2d8c634c191ebfd065a08db66cc6
901376
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s11033-023-08695-9.pdf