2026-06-03T08:19:15Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/280312026-02-03T10:58:38Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Martínez-Fernández, Diana Emilia
author
Fernández-Quezada, David
author
Casillas-Muñoz, Fidel Antonio Guadalupe
author
Carrillo-Ballesteros, Francisco Josué
author
Ortega-Prieto, Ana María
author
Jiménez-Guardeño, José Manuel
author
Regla-Nava, Jose Ángel
2023-11-15T10:33:25Z
2023-11-15T10:33:25Z
2023-07-18
https://hdl.handle.net/10630/28031
10.3390/pathogens12070947
Monkeypox virus (MPXV) is an emerging zoonotic virus that belongs to the Orthopoxvirus genus and presents clinical symptoms similar to those of smallpox, such as fever and vesicular-pustular skin lesions. However, the differential diagnosis between smallpox and monkeypox is that smallpox does not cause lymphadenopathy but monkeypox generates swelling in the lymph nodes. Since the eradication of smallpox, MPXV has been identified as the most common Orthopoxvirus to cause human disease. Despite MPXV being endemic to certain regions of Africa, the current MPXV outbreak, which began in early 2022, has spread to numerous countries worldwide, raising global concern. As of the end of May 2023, over 87,545 cases and 141 deaths have been reported, with most cases identified in non-endemic countries, primarily due to human-to-human transmission. To better understand this emerging threat, this review presents an overview of key aspects of MPXV infection, including its animal reservoirs, modes of transmission, animal models, epidemiology, clinical and immunological features, diagnosis, treatments, vaccines, and prevention strategies. The material presented here provides a comprehensive understanding of MPXV as a disease, while emphasizing the significance and unique characteristics of the 2022 outbreak. This offers valuable information that can inform future research and aid in the development of effective interventions.
eng
Atribución 4.0 Internacional
Viruela de los monos humana - Epidemiología
Viruela de los monos humana - Patogénesis
Viruela de los monos humana - Prevención
Zoonosis
Human Monkeypox: A Comprehensive Overview of Epidemiology, Pathogenesis, Diagnosis, Treatment, and Prevention Strategies.
journal article
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URL
https://riuma.uma.es/bitstreams/02a1499f-7b01-4c71-9f3e-6551b1b26d29/download
File
MD5
2026c81c698237e5fa43f394bae0387c
1302210
application/pdf
pathogens-12-00947 (1).pdf