2026-06-01T02:18:08Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/293962026-02-03T11:35:09Zcom_10630_2254col_10630_37953

00925njm 22002777a 4500 dc Sánchez-Molina, María author Díaz-Morilla, Amelia author Sauter, Eric author Zharnikov, Michael author López-Romero, Juan Manuel author 2018-11-09 We describe design and synthesis of novel tripod-shaped molecules that are potentially capable of monomolecular assembly on noble metal substrates, maintaining, due to their rigidity and specific geometry, the orientation of the functional arm in a perpendicular fashion with respect to the substrate. Using a combination of X-ray photoelectron spectroscopy, X-ray absorption spectroscopy and atomic force microscopy, the ability of these molecules to form well-defined and densely packed self-assembled monolayers (SAMs) on Au(111) was demonstrated, with the majority of the molecules adsorbed in the predefined tripodal geometry, relying on the thiolate-gold anchors. The functionality of the respective monomolecular templates was proved by click reaction between the terminal alkyne groups of the monolayers and complementary azide-substituted substituent (theophylline), which served potentially as specific protein receptor. The resulting theophylline-terminated films were successfully tested for specific protein adsorption, verifying the validity and reliability of the presented concept, in terms of the tripod design and its "activation" by the click reaction. María Sánchez-Molina, Amelia Díaz, Eric Sauter, Michael Zharnikov, J. Manuel López-Romero, Tripod-shaped molecules: Synthesis and immobilization on Au(1 1 1) substrates, Applied Surface Science, Volume 470, 2019, Pages 259-268, ISSN 0169-4332, https://doi.org/10.1016/j.apsusc.2018.11.013 https://hdl.handle.net/10630/29396 10.1016/j.apsusc.2018.11.013 Macromoléculas Reacciones químicas orgánicas Teofilina Superficies (Tecnología) - Análisis Tripod-shaped molecules: Synthesis and immobilization on Au(1 1 1) substrates.