2026-05-29T21:00:11Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/299372026-02-03T11:03:30Zcom_10630_2254col_10630_37953

Jiménez-Fernández, S. Gurpegui, Manuel Dí­az-Atienza, Francisco Pérez-Costillas, Lucía María Gerstenberg, Miriam Correll, Christoph U. 2024-02-07T07:18:51Z 2024-02-07T07:18:51Z 2015-12-23 Jiménez-Fernández, S., Gurpegui, M., Díaz-Atienza, F., Pérez-Costillas, L., Gerstenberg, M., & Correll, C. U. (2015). Oxidative Stress and Antioxidant Parameters in Patients With Major Depressive Disorder Compared to Healthy Controls Before and After Antidepressant Treatment. The Journal of Clinical Psychiatry, 76(12), 1658–1667. https://hdl.handle.net/10630/29937 10.4088/JCP.14r09179 Objective: To investigate the role of oxidative stress and antioxidants in depression. Data Sources: We searched the literature without language restrictions through MEDLINE/PubMed, Cochrane Library, Fisterra, and Galenicom from database inception until December 31, 2013, supplemented by a hand search of relevant articles. Search terms included (1) oxidative stress, antioxidant*, nitrosative stress, nitrative stress, nitro-oxidative stress, free radical*, and names of individual oxidative stress markers/antioxidants and (2) depression and related disorders and antidepressant. Study Selection: Included were studies in patients with depression comparing antioxidant or oxidative stress markers with those in healthy controls before and after antidepressant treatment. Data Extraction: Two authors independently extracted the data for antioxidant or oxidative stress markers. Standardized mean differences (SMDs) ± 95% confidence intervals (CIs) for results from ≥ 3 studies were calculated. eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Desórdenes mentales Depresión mental Antidepresivos Estrés oxidativo Oxidative stress and antioxidant parameters in patients with major depressive disorder compared to healthy controls before and after antidepressant treatment: results from a meta-analysis. journal article