2026-06-01T14:21:52Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/312502026-02-03T11:07:48Zcom_10630_2254col_10630_37953

00925njm 22002777a 4500 dc Gálvez Carvajal, Laura author Sánchez-Muñoz, Alfonso author Ribelles, Nuria author Saez, Maribel author Baena, Javier author Ruiz, Sofía author Ithurbisquy, Catherine author Alba-Conejo, Emilio author 2019 Germ cell tumors (GCTs) are the most common type of solid tumor amongst patients between 15 and 35 years of age. They are also one of the types of tumor with the highest cure rate, due to their high sensitivity to cisplatin based chemotherapy. Nonetheless, around 15-20% of metastatic patients will not have curative options after a relapse on the first and second line. This proves that new therapeutic options for these refractory GCTs patients need to be developed. This article offers a bibliographic review of all studies using targeted treatment or immunotherapy for refractory GCTs patients. Galvez-Carvajal L, Sanchez-Muñoz A, Ribelles N, Saez M, Baena J, Ruiz S, Ithurbisquy C, Alba E. Targeted treatment approaches in refractory germ cell tumors. Crit Rev Oncol Hematol. 2019 Nov;143:130-138. doi: 10.1016/j.critrevonc.2019.09.005. Epub 2019 Sep 25. PMID: 31634730. https://hdl.handle.net/10630/31250 10.1016/j.critrevonc.2019.09.005 Células germinales - Tumores Targeted treatment approaches in refractory germ cell tumors