2026-06-04T12:43:30Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/328232026-02-03T11:01:46Zcom_10630_2254col_10630_37953

Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus Ojeda-Pérez, Betsaida Campos-Sandoval, José Ángel García-Bonilla, María Cárdenas García, Casimiro Páez-González, Patricia Jiménez-Lara, Antonio Jesús Hidrocefalia Marcadores bioquímicos Periventricular extracellular oedema, myelin damage, inflammation, and glial reactions are common neuropathological events that occur in the brain in congenital hydrocephalus. The periventricular white matter is the most affected region. The present study aimed to identify altered molecular and cellular biomarkers in the neocortex that can function as potential therapeutic targets to both treat and evaluate recovery from these neurodegenerative conditions. The hyh mouse model of hereditary hydrocephalus was used for this purpose. 2024-09-23T09:22:11Z 2024-09-23T09:22:11Z 2021 journal article Ojeda-Pérez, B., Campos-Sandoval, J.A., García-Bonilla, M. et al. Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus. Fluids Barriers CNS 18, 30 (2021). https://doi.org/10.1186/s12987-021-00263-2 https://hdl.handle.net/10630/32823 10.1186/s12987-021-00263-2 eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional BMC