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      <dc:title>A cost minimization analysis of olive oil vs. hyperoxygenated fatty acid treatment for the prevention of pressure ulcers in primary healthcare: A randomized controlled trial</dc:title>
      <dc:creator>Lupiáñez-Pérez, Inmaculada</dc:creator>
      <dc:creator>Morilla-Herrera, Juan Carlos</dc:creator>
      <dc:creator>Kaknani-Uttumchandani, Shakira</dc:creator>
      <dc:creator>Lupiáñez Pérez, Yolanda</dc:creator>
      <dc:creator>Cuevas-Fernández-Gallego, María Magdalena</dc:creator>
      <dc:creator>Martín-Santos, Francisco Javier</dc:creator>
      <dc:creator>Caro-Bautista, Jorge</dc:creator>
      <dc:creator>Morales-Asencio, José Miguel</dc:creator>
      <dc:subject>Úlceras por presión</dc:subject>
      <dc:description>Pressure ulcers represent a major current health problem and cause an important&#xd;
economic impact on the healthcare system. Most studies on the prevention of&#xd;
pressure ulcers have been carried out in hospital contexts, with respect to the use&#xd;
of hyperoxygenated fatty acids (HOFA), and to date no studies have specifically&#xd;
examined the use of olive oil-based treatments. Aim: To evaluate the cost of&#xd;
using extra virgin olive oil, rather than HOFA, in the prevention of pressure&#xd;
ulcers among persons with impaired mobility and receiving home care. Study&#xd;
Design: Cost minimization analysis of the results obtained from a noninferiority,&#xd;
triple-blind, parallel, multicenter, randomized clinical trial. Population attending&#xd;
primary healthcare centers in Andalusia (Spain). Study sample: 831 immobilized&#xd;
patients at risk of suffering pressure ulcers. These persons were included in the&#xd;
study and randomly assigned as follows: 437 to the olive oil group and 394 to&#xd;
the HOFA group. At the end of the follow-up period, the results obtained by the&#xd;
olive oil group were not inferior to those of the HOFA group, and did not&#xd;
exceed the 10% delta limit. The total treatment cost for 16 weeks was e19,758&#xd;
with HOFAs and e9,566 with olive oil. Overall, the olive oil treatment was&#xd;
e10,192 less costly. It has been concluded the noninferiority of olive oil makes&#xd;
this product an effective alternative for the prevention of pressure ulcers in&#xd;
patients who are immobilized and in a domestic environment. This treatment&#xd;
enables considerable savings in direct costs.</dc:description>
      <dc:date>2024-09-29T18:05:59Z</dc:date>
      <dc:date>2024-09-29T18:05:59Z</dc:date>
      <dc:date>2017-08-15</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Lupiañez-Pérez I, Morilla-Herrera JC, Kaknani-Uttumchandani S, Lupiañez-Perez Y, Cuevas-Fernandez-Gallego M, Martin-Santos F, Caro-Bautista J, Morales-Asencio JM. A cost minimization analysis of olive oil vs. hyperoxygenated fatty acid treatment for the prevention of pressure ulcers in primary healthcare: A randomized controlled trial. Wound Repair Regen. 2017 Sep;25(5):846-851. doi: 10.1111/wrr.12586. Epub 2017 Nov 6. PMID: 28922519.</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10630/33930</dc:identifier>
      <dc:identifier>10.1111/wrr.12586</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>open access</dc:rights>
      <dc:publisher>Wiley</dc:publisher>
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