2026-05-30T15:48:35Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/339812026-02-03T11:05:27Zcom_10630_2254col_10630_37953

00925njm 22002777a 4500 dc Ramos-Petersen, Laura author Nester, Christopher author Reinoso-Cobo, Andrés author Nieto-Gil, Pilar author Ortega-Ávila, Ana Belén author Gijón-Noguerón, Gabriel author 2020 Abstract: Background and Objective: Ninety percent of patients with rheumatoid arthritis (RA) feel foot pain during the disease process. Pharmacological treatment of RA has a systematic effect on the body and includes: Nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs (DMARDs) and biologics. The objective of our review was to examine the impact of biologics on patients with RA ‘foot. Methods and Material: A systematic review of randomized control trials and observational studies that evaluated the efficacy of biologics against other pharmacological treatment, and included a foot outcome measure. The search covered MEDLINE Ovid, Pubmed, CINAHL, Cochrane Library, Evidence Search, and Web of Science. Risk of bias was evaluated using Cochrane guidance and the Newcastle Ottawa Scale adapted version. Results: A total of eight studies fully met the inclusion criteria: Three randomized control trials, and five observational studies were the basis of our review. A total sample of 1856 RA patients with RA treatment participated. The use of biologics was not associated as a risk factor for post-operative surgical site infection or delayed wound healing. The benefits of biologics, in terms of the disease evolution, were assessed using X-ray. Conclusion: Evidence suggests that the use of biologics is not a risk factor for post-operative surgical site infection or delayed wound healing. The use of biologics presents benefits in terms of the disease evolution assessed through X-ray. Ramos-Petersen, L.; Nester, C.J.; Reinoso-Cobo, A.; Nieto-Gil, P.; Ortega-Avila, A.B.; Gijon-Nogueron, G. ASystematic Review to Identify the Effects of Biologics in the Feet of Patients with Rheumatoid Arthritis. Medicina 2021, 57, 23. https://doi.org/10.3390/ medicina57010023. PMID: 33383830; PMCID: PMC7824565. https://hdl.handle.net/10630/33981 10.3390/medicina57010023 Artritis reumatoide Productos biológicos - Uso terapéutico A Systematic Review to Identify the Effects of Biologics in the Feet of Patients with Rheumatoid Arthritis