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oai:riuma.uma.es:10630/344122026-02-03T11:21:48Zcom_10630_2254col_10630_37953

Nervous necrosis virus (NNV) vaccination of carrier Senegalese sole (Solea senegalensis). Souto, Sandra Olveira, José López-Vázquez, Carmen Dopazo, Carlos Labella Vera, Alejandro Manuel Bandin, Isabel Virus con ARN Lenguados Senegalese sole Nervous necrosis virus NNV carrier Immune response Vaccination Viral encephalopathy and retinopathy (VER), caused by nervous necrosis virus (NNV), is one of the most threatening diseases affecting marine farmed fish, especially in early developmental stages. In addition, subclinical infections are commonly detected in both farmed and wild fish. In recent years numerous efforts have been made to achieve effective vaccines for the protection of different fish species against NNV infection. Vaccination experiments are always conducted on pathogen-free animals, but subclinically infected individuals may respond differently to immunization. In this study, we have observed a different response between experimentally-induced-NNV carrier Senegalese sole and NNV-free animals when immunized with a BEIinactivated vaccine, whereas mock-vaccinated carrier fish behaved like the NNV-free group. This research was funded by Ministerio de Ciencia, Innovación y Universidades (MICIU), the Agencia Estatal de Investigación (AEI) and FEDER, grant number RTI2018-094687-B-C21 . Dr. Sandra Souto was funded with a postdoctoral grant from Consellería de Cultura, Educación y Universidad, Xunta de Galicia (postdoctoral grant ED481D-2022/024 ). The authors are grateful to Stolt Sea Farm for kindly providing the fish, J. Franqueira for technical assistance and Native English School of Languages for the English revision. 2024-10-07T09:43:27Z 2024-10-07T09:43:27Z 2023 journal article VoR Sandra Souto, Jose G. Olveira, Carmen López-Vázquez, Carlos P. Dopazo, Alejandro Labella, Isabel Bandín, Nervous necrosis virus (NNV) vaccination of carrier Senegalese sole (Solea senegalensis), Aquaculture, Volume 579, 2024, 740211, ISSN 0044-8486, https://doi.org/10.1016/j.aquaculture.2023.740211. (https://www.sciencedirect.com/science/article/pii/S0044848623009857) https://hdl.handle.net/10630/34412 10.1016/j.aquaculture.2023.740211. eng Attribution-NonCommercial 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0/ open access application/pdf Elsevier