2026-06-01T11:32:10Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/344752026-02-03T11:30:17Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Lees, Jonathan
author
Yeats, Corin
author
Perkins, James Richard
author
Sillitoe, Ian
author
Rentzsch, Robert
author
Dessailly, Benoit H
author
Orengo, Christine A.
2024-10-08T08:37:40Z
2024-10-08T08:37:40Z
2012-01
Jonathan Lees, Corin Yeats, James Perkins, Ian Sillitoe, Robert Rentzsch, Benoit H. Dessailly, Christine Orengo, Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis, Nucleic Acids Research, Volume 40, Issue D1, 1 January 2012, Pages D465–D471, https://doi.org/10.1093/nar/gkr1181
https://hdl.handle.net/10630/34475
10.1093/nar/gkr1181
Gene3D http://gene3d.biochem.ucl.ac.uk is a comprehensive database of protein domain assignments for sequences from the major sequence databases. Domains are directly mapped from structures in the CATH database or predicted using a library of representative profile HMMs derived from CATH superfamilies. As previously described, Gene3D integrates many other protein family and function databases. These facilitate complex associations of molecular function, structure and evolution. Gene3D now includes a domain functional family (FunFam) level below the homologous superfamily level assignments. Additions have also been made to the interaction data. More significantly, to help with the visualization and interpretation of multi-genome scale data sets, we have developed a new, revamped website. Searching has been simplified with more sophisticated filtering of results, along with new tools based on Cytoscape Web, for visualizing protein-protein interaction networks, differences in domain composition between genomes and the taxonomic distribution of individual superfamilies.
eng
Atribución-NoComercial 4.0 Internacional
Proteínas-Bases de datos
Proteínas-Clasificación
Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis
journal article
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gene3D.pdf