2026-06-05T14:24:02Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/345032026-02-03T11:33:42Zcom_10630_2254col_10630_37953

Peripheral membrane proteins modulate stress tolerance by safeguarding cellulose synthases Kesten, Christopher García-Moreno, Álvaro Amorim-Silva, Vitor Menna, Alexandra Castillo-Garriga, Araceli Percio, Francisco Armengot, Laia Ruiz-López, Noemí Jaillais, Yvon Sánchez-Rodríguez, Clara Botella-Mesa, Miguel Ángel Celulosa-Síntesis Controlled primary cell wall remodeling allows plant growth under stressful conditions, but how these changes are conveyed to adjust cellulose synthesis is not understood. Here, we identify the TETRATRICOPEPTIDE THIOREDOXIN-LIKE (TTL) proteins as new members of the cellulose synthase complex (CSC) and describe their unique and hitherto unknown dynamic association with the CSC under cellulose-deficient conditions. We find that TTLs are essential for maintaining cellulose synthesis under high-salinity conditions, establishing a stress-resilient cortical microtubule array, and stabilizing CSCs at the plasma membrane. To fulfill these functions, TTLs interact with CELLULOSE SYNTHASE 1 (CESA1) and engage with cortical microtubules to promote their polymerization. We propose that TTLs function as bridges connecting stress perception with dynamic regulation of cellulose biosynthesis at the plasma membrane. 2024-10-08T10:57:12Z 2024-10-08T10:57:12Z 2022-11-16 journal article Christopher Kesten et al. ,Peripheral membrane proteins modulate stress tolerance by safeguarding cellulose synthases.Sci. Adv.8,eabq6971(2022).DOI:10.1126/sciadv.abq6971 https://hdl.handle.net/10630/34503 10.1126/sciadv.abq6971 eng open access American Association for the Advancement of Science