2026-05-31T08:19:47Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/355222026-02-03T11:14:28Zcom_10630_2254col_10630_37953

00925njm 22002777a 4500 dc Gomez-Casado, Gema author Jimenez-Gonzalez, Andrés author Rodríguez-Muñoz, Alba author Tinahones-Madueño, Francisco José author González-Mesa, Ernesto Santiago author Murri, Mora author 2024 Introduction: The aim of this study is to evaluate and compare the suitability of rou-tine blood neutrophil values as indicators of obesity-associated inflammation.Methods: In this systematic review and meta-analysis, we assess absolute neutrophilcounts (ANCs) and neutrophil-to-lymphocyte ratio (NLR) values in subjects with andwithout obesity and analyze the weight of both parameters on the disease. Addition-ally, correlation studies between ANC and NLR with BMI, a parameter internationallyaccepted to define obesity are performed.Results: Quantitative data from 12 (ANC) and 11 (NLR) studies were included, with atotal of 4475 participants. The meta-analysis shows that while both parameters areincreased in the obesity group, ANC values present higher differences with the con-trol and less heterogeneity among studies. Additionally, unlike NLR, ANC demon-strates a positive and significant correlation with BMI.Conclusion: Overall, this meta-analysis demonstrates that ANC is a more reliable andstable parameter than NLR for the assessment of obesity-related inflammation, whichoffers clinicians a novel tool to assist in preventing complications related to obesity Gomez-Casado G, Jimenez-Gonzalez A, Rodriguez-Muñoz A, et al. Neutrophils as indicators of obesity-associated inflammation: A systematic review and meta-analysis. Obesity Reviews. 2024;e13868. doi:10.1111/obr.13868 https://hdl.handle.net/10630/35522 https://doi.org/10.1111/obr.13868 Obesidad Neutrófilos Neutrophils as indicators of obesity-associated inflammation: a systematic review and meta-analysis.