2026-05-28T07:46:50Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/358972026-02-03T12:30:55Zcom_10630_2254col_10630_37959
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Burgos-Molina, Antonio Manuel
author
Rodríguez-García, Marta
author
González-Vidal, Alejandro
author
Mercado-Sáenz, Silvia
author
Ruiz-Gómez, Miguel José
2025-01-07T12:39:23Z
2025-01-07T12:39:23Z
2024
https://hdl.handle.net/10630/35897
Analysis of the response to radiation of tumor biopsies can provide very valuable information about the possible resistance of colorectal cancer to treatment. Resistance mechanisms involve overexpression of the CREB-KDM4B-STAT3 axis, as well as alterations in the expression of BEX1 and BTG3. It is important to highlight the increase in DNA repair and decrease in apoptosis by RAD50 and IGF-1R.
New therapies based on the use of molecular response markers and new therapeutic targets that address radiation resistance would be very useful for the individualization of treatments and precision medicine.
eng
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Cáncer - Prevención
Cáncer colorrectal
Biopsia
Response to radiation in tumor biopsies from colorectal cancer patients.
conference output
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URL
https://riuma.uma.es/bitstreams/530ddea0-8da7-4e8d-a280-687514110998/download
File
MD5
b45a56b6e7f837570c441ef7974bbee2
75521
application/pdf
6- RR tumor biopsies.pdf