2026-05-27T05:36:30Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/371752026-02-03T11:01:48Zcom_10630_2254col_10630_37953

Sanjuan-Jimenez, Rocio Morata-Losa, María Pilar Bermúdez, Pilar Bravo-Romero, María José Colmenero Castillo, Juan de Dios 2025-01-28T11:35:46Z 2025-01-28T11:35:46Z 2013-12-12 Sanjuan-Jimenez R, Morata P, Bermúdez P, Bravo MJ, Colmenero JD (2013) Comparative Clinical Study of Different Multiplex Real Time PCR Strategies for the Simultaneous Differential Diagnosis between Extrapulmonary Tuberculosis and Focal Complications of Brucellosis. PLoS Negl Trop Dis 7(12): e2593. https://doi.org/10.1371/journal.pntd.0002593 https://hdl.handle.net/10630/37175 10.1371/journal.pntd.0002593. Background Both brucellosis and tuberculosis are chronic-debilitating systemic granulomatous diseases with a high incidence in many countries in Africa, Central and South America, the Middle East and the Indian subcontinent. Certain focal complications of brucellosis and extrapulmonary tuberculosis are very difficult to differentiate clinically, biologically and radiologically. As the conventional microbiological methods for the diagnosis of the two diseases have many limitations, as well as being time-consuming, multiplex real time PCR (M RT-PCR) could be a promising and practical approach to hasten the differential diagnosis and improve prognosis eng open access Reacción en cadena de la polimerasa Tuberculosis - Diagnóstico Brucelosis - Diagnóstico Comparative Clinical Study of Different Multiplex Real Time PCR Strategies for the Simultaneous Differential Diagnosis between Extrapulmonary Tuberculosis and Focal Complications of Brucellosis. journal article