2026-05-27T12:56:02Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/371992026-02-03T10:58:34Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Burgos-Molina, Antonio Manuel
author
Téllez-Santana, Teresa
author
Redondo-Bautista, Maximino
author
Bravo-Romero, María José
2025-01-28T12:50:07Z
2025-01-28T12:50:07Z
2024
Burgos-Molina, A.M.; Téllez Santana, T.; Redondo, M.; Bravo Romero, M.J. The Crucial Role of Inflammation and the Immune System in Colorectal Cancer Carcinogenesis: A Comprehensive Perspective. Int. J. Mol. Sci. 2024, 25, 6188. https://doi.org/10.3390/ijms25116188
https://hdl.handle.net/10630/37199
10.3390/ijms25116188
Chronic inflammation drives the growth of colorectal cancer through the dysregulation of molecular pathways within the immune system. Infiltration of immune cells, such as macrophages, into tumoral regions results in the release of proinflammatory cytokines (IL-6; IL-17; TNF-α), fostering tumor proliferation, survival, and invasion. Tumors employ various mechanisms to evade immune surveillance, effectively ‘cloaking’ themselves from detection and subsequent attack. A comprehensive understanding of these intricate molecular interactions is paramount for advancing novel strategies aimed at modulating the immune response against cancer.
eng
Colon (Anatomía) - Cáncer
Inflamación (Patología)
The Crucial Role of Inflammation and the Immune System in Colorectal Cancer Carcinogenesis: A Comprehensive Perspective.
journal article
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URL
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File
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1234817
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burgos2024.pdf