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      <dc:title>Predictive model to identify the risk of losing protective sensibility of the foot in patients with diabetes mellitus.</dc:title>
      <dc:creator>Chicharro-Luna, Esther</dc:creator>
      <dc:creator>Pomares-Gómez, Francisco Javier</dc:creator>
      <dc:creator>Ortega-Ávila, Ana Belén</dc:creator>
      <dc:creator>Marchena-Rodríguez, Ana José</dc:creator>
      <dc:creator>Blanquer-Gregori, José</dc:creator>
      <dc:creator>Navarro-Flores, Emmanuel María</dc:creator>
      <dc:subject>Neuropatía diabética</dc:subject>
      <dc:subject>Pie diabético</dc:subject>
      <dc:subject>Diabetes</dc:subject>
      <dc:subject>Medicina - Modelos matemáticos</dc:subject>
      <dc:description>https://openpolicyfinder.jisc.ac.uk/id/publication/7033</dc:description>
      <dc:description>Diabetic neuropathy is defined as the presence of symptoms and signs of&#xd;
peripheral nerve dysfunction in diabetics. The aim of this study is to develop a&#xd;
predictive logistic model to identify the risk of losing protective sensitivity in&#xd;
the foot. This descriptive cross-sectional study included 111 patients diagnosed&#xd;
with diabetes mellitus. Participants completed a questionnaire designed to&#xd;
evaluate neuropathic symptoms, and multivariate analysis was subsequently&#xd;
performed to identify an optimal predictive model. The explanatory capacity&#xd;
was evaluated by calculating the R2 coefficient of Nagelkerke. Predictive capacity&#xd;
was evaluated by calculating sensitivity, specificity, and estimation of the&#xd;
area under the receiver operational curve. Protective sensitivity loss was&#xd;
detected in 19.1% of participants. Variables associated by multivariate analysis&#xd;
were: educational level (OR: 31.4, 95% CI: 2.5-383.3, P = .007) and two items&#xd;
from the questionnaire: one related to bleeding and wet socks (OR: 28.3, 95%&#xd;
CI: 3.7-215.9, P = .001) and the other related to electrical sensations (OR: 52.9,&#xd;
95% CI: 4.3-643.9, P = .002), which were both statistically significant. The predictive&#xd;
model included the variables of age, sex, duration of diabetes, and educational&#xd;
level, and it had a sensitivity of 81.3% and a specificity of 95.5%. This&#xd;
model has a high predictive capacity to identify patients at risk of developing&#xd;
sensory neuropathy.</dc:description>
      <dc:date>2025-04-11T10:46:06Z</dc:date>
      <dc:date>2025-04-11T10:46:06Z</dc:date>
      <dc:date>2019</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Chicharro-Luna E, Pomares-Gómez FJ, Ortega-Ávila AB, Marchena-Rodríguez A, Blanquer-Gregori JFJ, Navarro-Flores E. Predictive model to identify the risk of losing protective sensibility of the foot in patients with diabetes mellitus. Int Wound J. 2020 Feb;17(1):220-227. doi: 10.1111/iwj.13263. Epub 2019 Nov 5. PMID: 31691513; PMCID: PMC7949069.</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10630/38440</dc:identifier>
      <dc:identifier>10.1111/iwj.13263</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>open access</dc:rights>
      <dc:publisher>Wiley</dc:publisher>
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