2026-05-31T18:56:17Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/389412026-04-10T08:28:47Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Huércano Rubens, Carolina
author
Moya-Barrientos, Miriam
author
Cuevas Corral, Oliver
author
Sánchez-Vera, Victoria
author
Ruiz-López, Noemí
2025-06-09T11:02:12Z
2025-06-09T11:02:12Z
2025-05-22
Huercano C, Moya-Barrientos M, Cuevas O, Sanchez-Vera V, Ruiz-Lopez N. ER-plastid contact sites as molecular crossroads for plastid lipid biosynthesis. BMC Biol. 2025 May 22;23(1):139. doi: 10.1186/s12915-025-02239-2. PMID: 40405194; PMCID: PMC12096540.
https://hdl.handle.net/10630/38941
10.1186/s12915-025-02239-2
Membrane contact sites are specialized regions where organelle membranes are in close proximity, enabling lipid transfer while preserving membrane identity. In plants, ER‒chloroplast contact sites are critical for maintaining glycerolipid homeostasis. This review examines the lipid-modifying and lipid-transfer proteins/complexes involved in these processes. Key proteins at these sites, including components of the TGD and VAP27‒ORP2A complexes, as well as Sec14 proteins, facilitate lipid exchange. Additionally, the roles of lipid-modifying proteins at these contact sites are discussed. Despite significant progress, further research is needed to identify additional proteins, investigate ER‒chloroplast dynamics under stress and explore ER contact sites in non-chloroplast plastids.
eng
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Membranas (Biología)
Lípidos de membrana
Retículo endoplásmico
ER-plastid contact sites as molecular crossroads for plastid lipid biosynthesis
journal article
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