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oai:riuma.uma.es:10630/392202026-02-03T11:14:16Zcom_10630_2254col_10630_37953

Synaptic tagging during memory allocation. Rogerson, Thomas Cai, Denise J. Frank, Adam Sano, Yoshitake Shobe, Justin López-Aranda, Manuel Francisco Silva, Alcino J. Memoria - Aspectos fisiológicos Sinapsis Neurociencias There is now compelling evidence that the allocation of memory to specific neurons (neuronal allocation) and synapses (synaptic allocation) in a neurocircuit is not random and that instead specific mechanisms, such as increases in neuronal excitability and synaptic tagging and capture, determine the exact sites where memories are stored. We propose an integrated view of these processes, such that neuronal allocation, synaptic tagging and capture, spine clustering and metaplasticity reflect related aspects of memory allocation mechanisms. Importantly, the properties of these mechanisms suggest a set of rules that profoundly affect how memories are stored and recalled. 2025-07-02T12:08:30Z 2025-07-02T12:08:30Z 2025-07-02T12:08:30Z 2014-02-05 journal article Rogerson, T., Cai, D., Frank, A. et al. Synaptic tagging during memory allocation. Nat Rev Neurosci 15, 157–169 (2014). https://doi.org/10.1038/nrn3667 https://hdl.handle.net/10630/39220 10.1038/nrn3667 eng open access Nature