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      <dc:title>Feasibility of Home-Based Early Infant Hybrid Therapy in Children with Unilateral Cerebral Palsy</dc:title>
      <dc:creator>Palomo‐Carrión, Rocío</dc:creator>
      <dc:creator>Romay Barrero, Helena Maria</dc:creator>
      <dc:creator>Pinero‐Pinto, Elena</dc:creator>
      <dc:creator>Romero-Galisteo, Rita Pilar</dc:creator>
      <dc:creator>Coello-Villalón, María</dc:creator>
      <dc:creator>Ferri-Morales, Asunción</dc:creator>
      <dc:creator>López-Muñoz, Purificación</dc:creator>
      <dc:creator>Lirio-Romero, Cristina</dc:creator>
      <dc:subject>Niños paralíticos cerebrales - Ejercicios terapéuticos</dc:subject>
      <dc:subject>Neuroplasticidad</dc:subject>
      <dc:description>The first stage of childhood is characterized by great neuronal plasticity. In&#xd;
Unilateral Cerebral Palsy (UCP), it is essential to carry out early treatment, with family involvement.&#xd;
The aim of this study was to investigate the feasibility of Early Infant Hybrid Therapy (eI-Hybrid) applied&#xd;
at home with family involvement in children with UCP aged 9–18 months, and to assess its preliminary&#xd;
effectiveness on bimanual functional performance. Methods: A single group of 10 children&#xd;
(12.8 months, SD = 3.4) performed the eI-Hybrid therapy. The main outcome was measured with&#xd;
the mini Assisting Hand Assessment scale (mini-AHA), functional goals were measured with the&#xd;
Goal Attainment Scale (GAS), and satisfaction expectations on intensive therapy were also recorded.&#xd;
Three measures were performed (week 0, week 10, and month 6). A repeated-measures ANOVA&#xd;
test was performed on the mini-AHA in order to observe the statistically significant differences&#xd;
in pairwise comparison. Results: Ten children completed the study and the parents’ expectations&#xd;
were fulfilled, indicating high caregiver compliance and high adherence to the treatment. Clinically&#xd;
relevant changes were observed between pre- and post-intervention measurements in BFP (pre: 41.9&#xd;
(SD: 7.7), post: 50.9 (SD: 6.0) and in the follow-up at 6 months (50.3 (SD:5.6); p &lt; 0.001). Families&#xd;
reported a high satisfaction. Conclusions: infant hybrid treatment is feasible to be performed at home&#xd;
with the family’s involvement, obtaining improvements in the affected upper limb for early-age UCP</dc:description>
      <dc:date>2025-07-28T11:25:08Z</dc:date>
      <dc:date>2025-07-28T11:25:08Z</dc:date>
      <dc:date>2024</dc:date>
      <dc:type>journal article</dc:type>
      <dc:identifier>Palomo-Carrión, R., Romay-Barrero, H., Pinero-Pinto, E., Romero-Galisteo, R. P., Coello-Villalón, M., Ferri-Morales, A., ... &amp; Lirio-Romero, C. (2024). Feasibility of Home-Based Early Infant Hybrid Therapy in Children with Unilateral Cerebral Palsy. Journal of Clinical Medicine, 13(22), 6725.</dc:identifier>
      <dc:identifier>https://hdl.handle.net/10630/39543</dc:identifier>
      <dc:identifier>10.3390/jcm13226725</dc:identifier>
      <dc:language>eng</dc:language>
      <dc:rights>open access</dc:rights>
      <dc:publisher>MDPI</dc:publisher>
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