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oai:riuma.uma.es:10630/398392026-02-03T11:18:00Zcom_10630_2254col_10630_37953

Ocaña, Mª Carmen Bernal, Manuel Rodríguez-Quesada, Ana María Medina-Torres, Miguel Ángel 2025-09-11T08:18:54Z 2025-09-11T08:18:54Z 2025-10 Ocaña, M. C., Bernal, M., Quesada, A. R., & Medina, M. Á. (2025). A primer on metabolic contributions in tumor angiogenic microenvironment. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 189417. https://hdl.handle.net/10630/39839 10.1016/j.bbcan.2025.189417 Angiogenesis and metabolic remodeling are two hallmarks of cancer. This review aims to synthesize the current scientific literature linking these two processes, providing an overview of the principal metabolic mechanisms that contribute to the tumor angiogenic microenvironment. Additionally, it highlights metabolic remodeling as a promising therapeutic target for the treatment of angiogenesis-dependent pathologies, including different kinds of cancer. Finally, future directions for research on the field are suggested based on new working hypotheses. eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 Internacional Biología molecular Bioquímica Cáncer Células cancerosas Neovascularización A primer on metabolic contributions in tumor angiogenic microenvironment journal article