2026-06-02T02:03:09Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/399022026-02-03T11:31:38Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
González-Palacios Torres, Carla
author
Muñoz-Bravo, Carlos
author
Puebla, Iratxe inés
author
Castillo-Hermoso, María Ángeles
author
Toledo, Estefanía
author
Dierssen, Trinidad
author
Jiménez-Moleón, José Juan
author
Barrios-Rodríguez, Rocío
2025-09-15T09:40:13Z
2025-09-15T09:40:13Z
2025-08-14
Carla González-Palacios Torres, Carlos Muñoz-Bravo, Iratxe Inés Puebla, María Ángeles Castillo-Hermoso, Estefanía Toledo, Trinidad Dierssen-Sotos, José Juan Jiménez-Moleón, Rocío Barrios-Rodríguez, Long-Term Effectiveness of Dietary Interventions on Inflammatory Biomarkers in Women with Breast Cancer: A Systematic Review and Meta-Analysis, Nutrition Reviews, 2025;, nuaf137, https://doi.org/10.1093/nutrit/nuaf137
https://hdl.handle.net/10630/39902
10.1093/nutrit/nuaf137
Context: Improving the prognosis of breast cancer remains a challenge despite
the reduction in its mortality rates. Inflammatory parameters have been suggested
as prognostic biomarkers of cancer. A healthy diet could potentially modify these
factors; however, to date, findings have been inconclusive.
Objective: This review was conducted to estimate the strength of the association
between healthy dietary interventions and inflammatory markers in women with
breast cancer after a minimum 6-month follow-up.
Data Sources: The following literature databases were searched: MEDLINE,
Embase, Scopus, Web of Science, and the Cochrane Library.
Data Extraction: Clinical trials that compared the effect of dietary interventions
on the inflammatory profile of patients with breast cancer were selected. Quality
was assessed using the Cochrane Collaboration risk-of-bias tool. Two researchers
independently selected and evaluated the quality of the studies based on eligibility
criteria.
Data Analysis: Mean differences between intervention groups and their 95% CIs
were calculated using a random-effects model. The presence of heterogeneity was
analyzed with Cochran’s Q test, and I2 was estimated. Funnel plots and Egger’s
test were used to assess publication bias.
Results: A total of 11 trials were included in the meta-analysis. Adherence to a
healthy diet significantly decreased C-reactive protein (CRP) levels compared with
the control group (standard mean difference =–0.17; 95% CI –0.32 to –0.02; I2 =
0.00%). This result was maintained in the interventions focused on weight loss,
including only patients with overweight, those incorporating physical activity,
when follow-up was restricted to 6 months, and with interventions lasting at least
6 months
eng
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Mamas -- Cáncer
Dieta en enfermedades
Marcadores bioquímicos
Inflamación
Ejercicio físico
Long-Term Effectiveness of Dietary Interventions on Inflammatory Biomarkers in Women with Breast Cancer: A Systematic Review and Meta-Analysis
journal article
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