2026-05-31T02:36:40Zhttps://riuma.uma.es/rest/oai/request

oai:riuma.uma.es:10630/406522026-02-03T11:31:15Zcom_10630_2254col_10630_37953

00925njm 22002777a 4500 dc González Vidal, Alejandro author Mercado-Sáenz, Silvia author López-Díaz, Beatriz author Burgos-Molina, Antonio Manuel author González-Pedrosa, María Pilar author Sendra-Portero, Francisco author Ruiz-Gómez, Miguel José author 2025-11-03 This study aims to review the effects of radiation and SARS-CoV-2 infection on the gut microbiota, and the relationship it forms with the immune system and body axes. The intestinal microbiota is established after birth, reaching its greatest diversity in adulthood. It can be altered by factors which will depend on the host and the microorganisms. This work reviews how radiation and SARS-CoV-2 infection impact the microbiota, along with the connections established with body axes and immune system. The gut microbiota has important implications in health due to its role in multiple metabolic, physiological, and immune functions. The interaction with non-pathogenic microorganisms is beneficial; however, can cause diseases like cancer, obesity, diabetes or intestinal bowel disease. Recently, a direct relationship between microbiota and exposure to radiation in cancer patients, SARS-CoV-2 infection or different distal diseases induced via several corporal axes have been described. Microbiota acts as an independent organ, performing physiological, metabolic and immune functions; being beneficial or harmful to host. González-Vidal A., Mercado-Sáenz S., López-Díaz B., Burgos-Molina A.M., González-Pedrosa M.P., Sendra-Portero F., Ruiz-Gómez M.J. Radiation and SARS-CoV-2 effects on the microbiota, immune system and health. Indian J. Exp. Biol. 2025, 63:625-633. DOI: 10.56042/ijeb.v63i08.17900 https://hdl.handle.net/10630/40652 10.56042/ijeb.v63i08.17900 Radiación - Efectos fisiológicos Respuesta inmune Flora intestinal COVID-19 Radiation and SARS-CoV-2 effects on the microbiota, immune system and health