2026-06-02T05:18:26Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/462812026-04-08T23:45:34Zcom_10630_2254col_10630_37953
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Díaz-Román, Amparo
author
Zhang, Junhua
author
Delorme, Richard
author
Beggiato, Anita
author
Cortese, Samuele
2026-04-08T09:13:41Z
2018-10-25
Díaz-Román, A., Zhang, J., Delorme, R., Beggiato, A., & Cortese, S. (2018). Sleep in youth with autism spectrum disorders: Systematic review and meta-analysis of subjective and objective studies. Evidence-Based Mental Health, 21(4), 146–154. https://doi.org/10.1136/ebmental-2018-300037
https://hdl.handle.net/10630/46281
10.1136/ebmental-2018-300037
Background: Sleep problems are common and impairing in individuals with autism spectrum disorders (ASD). Evidence synthesis including both subjective (ie, measured with questionnaires) and objective (ie, quantified with neurophysiological tools) sleep alterations in youth with ASD is currently lacking.
Objective: We conducted a systematic review and meta-analysis of subjective and objective studies sleep studies in youth with ASD.
Methods: We searched the following electronic databases with no language, date or type of document restriction up to 23 May 2018: PubMed, PsycInfo, Embase+Embase Classic, Ovid Medline and Web of Knowledge. Random-effects models were used. Heterogeneity was assessed with Cochran's Q and I2 statistics. Publication (small studies) bias was assessed with final plots and the Egger's test. Study quality was evaluated with the Newcastle Ottawa Scale. Analyses were conducted using Review Manager and Comprehensive Meta-Analysis. FINDINGS: From a pool of 3359 non-duplicate potentially relevant references, 47 datasets were included in the meta-analyses. Subjective and objective sleep outcome measures were extracted from 37 and 15 studies, respectively. Only five studies were based on comorbidity free, medication-naïve participants. Compared with typically developing controls, youth with ASD significantly differed in 10/14 subjective parameters and in 7/14 objective sleep parameters. The average quality score in the Newcastle-Ottawa Scale was 5.9/9.
Discussion and clinical implications: A number of subjective and, to a less extent, objective sleep alterations might characterise youth with ASD, but future studies should assess the impact of pharmacological treatment and psychiatric comorbidities.
eng
Trastornos del espectro autista
Sueño - Trastornos en adolescentes
Sleep in youth with autism spectrum disorders: Systematic review and meta-analysis of subjective and objective studies
journal article
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Sleep in youth with ASD.pdf