2026-06-07T07:13:28Zhttps://riuma.uma.es/rest/oai/requestoai:riuma.uma.es:10630/73612026-02-03T11:48:18Zcom_10630_2254col_10630_37959
RIUMA. Repositorio Institucional de la Universidad de Málaga
author
Nieto-Ortega, Belén
author
Hierrezuelo-Osorio, José Manuel
author
Carnero-Ruiz, Cristóbal
author
López-Navarrete, Juan Teodomiro
author
Casado-Cordón, Juan
author
Ramírez-Aguilar, Francisco Javier
2014-03-31T11:56:02Z
2014-03-31T11:56:02Z
2014-03-31
http://hdl.handle.net/10630/7361
Protein denaturation by surfactants is related with topic as pharmaceutics, cosmetics, paints or biotechnology. This phenomenon is highly dependent on the physico-chemical properties of the denaturing agents. In this communication we report the ROA spectra of bovine serum albumin in the presence of different surfactants, which share a common hydrophobic tail, with the objerctive of correlating the structural specificities of the surfactant-protein interaction with the ROA signatures by following the protein unfolding process.In our work we propose two new groups of ROA marker bands related with the protein unfolding induced by surfactants. This work represents one of the first applications of ROA to study the interaction of a protein with surfactants, and a new proof of the ability of this chiroptical technique to see beyond that can be seen with conventional Raman spectroscopy.
eng
Espectroscopía Raman
Raman Optical Activity Monitoring the Interaction of Globular Proteins with Surfactants
conference output
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URL
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File
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application/pdf
icors2014_FJRamirez.pdf
URL
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File
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text/plain
icors2014_FJRamirez.pdf.txt