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AD0157, a pyrrolidinedione fungal metabolite, inhibits angiogenesis by targeting the Akt signaling pathway
García-Caballero, Melissa; Cañedo, Librada; Fernández-Medarde, Antonio; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2014-09-16)In the course of a screening program for the inhibitors of angiogenesis from marine sources, AD0157, a pyrrolidinedione fungal metabolite, was selected for its angiosupressive properties. AD0157 inhibited the growth of ...