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Listar por autor "Pineda-Gomez, Juan Pedro"
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A new pharmacological strategy against treatment-resistant depression
Pineda-Gomez, Juan Pedro; Millón-Peñuela, Carmelo; Cantero García, Noelia; Flores, Marta; Ladrón de Guevara-Miranda, David; Flores-Burgess, Antonio; Díaz-Cabiale, Zaida[et al.] (Elsevier, 2024)Major depressive disorder affects more than 50 million people in the world. However, 50% of patients don’t respond to two or more drugs or psychotherapeutic treatments, named treatment-resistant depression (TRD). In this ... -
Galanin (1-15) enhances the effects of Fluoxetine in an animal model of depression. Role of the 5-HT1A receptor.
Pineda-Gómez, Juan Pedro; Flores-Burgess, Antonio; Millón-Peñuela, Carmelo; Cantero-García, Noelia; Flores Gómez, Marta; Puigcerver-Martínez, Araceli; Díaz-Cabiale, Zaida[et al.] (2023)Major depression is one of the most significant contributors to global disability. Selective serotoninergicreuptake inhibitors, including Fluoxetine (FLX), are the most commonly used antidepressant but are onlyeffective ... -
Galanin N-terminal fragment (1-15) reduces alcohol consumption in the self-administration with involvement of mesocorticolimbic system in rats.
Cantero-García, Noelia; Flores Gómez, Marta; Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Orio, Laura; Serrano, Antonia; Díaz-Cabiale, Zaida; Millón-Peñuela, Carmelo[et al.] (2023)Alcohol Use Disorder (AUD) is a highly prevalent disorder characterized by an impaired ability tostop or control alcohol use despite the adverse consequences. Nowadays, AUD treatment is limiteddue to the low efficacy of ... -
Galanin N-terminal fragment (1− 15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system: dataset
Cantero-García, Noelia; Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Orio, Laura; Serrano, Antonia; Díaz-Cabiale, Zaida; Millón-Peñuela, Carmelo[et al.] (Universidad de Málaga, 2022)Alcohol Use Disorder (AUD) is among the most prevalent mental illnesses, and due to the low efficacy of the current medication, it is essential to find new biological targets that could modulate alcohol consumption. Since ... -
Galanin N-terminal fragment (1−15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system
Cantero-García, Noelia; Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Orio, Laura; Serrano, Antonia; Díaz-Cabiale, Zaida; Millón-Peñuela, Carmelo[et al.] (Elsevier, 2022-09)Alcohol Use Disorder (AUD) is among the most prevalent mental illnesses, and due to the low efficacy of the current medication, it is essential to find new biological targets that could modulate alcohol consumption. Since ... -
New augmentation strategy in depression: Galanin (1-15) enhances the behavioral effects of Fluoxetine in the olfactory bulbectomy rat.
Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Millón-Peñuela, Carmelo; Gago-Calderón, Belén; García-Durán, Laura; Cantero-García, Noelia; Puigcerver-Martínez, Araceli; Narváez-Bueno, José Ángel; Fuxe, Kjell; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2022-07-12)Major depression is the largest contributor to global disability by years lived with disability. Selective serotonergic reuptake inhibitors, including fluoxetine (FLX), are the most commonly used antidepressant for the ... -
The combination of Galanin (1-15) and Escitalopram decrease the alcohol selfadministration in rats through the functional network ventral tegmental area – dorsal raphe.
Flores Gómez, Marta; García-Cantero, Noelia; Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Serrano, Antonia; Orio, Laura; Puigcerver-Martínez, Araceli; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida; Millón-Peñuela, Carmelo[et al.] (2023)Alcohol Use Disorder AUD is a highly prevalent, and most AUD patients suffer comorbidity with depression. To investigate the effect of GAL(1-15) on ESCmediated effect in depression-alcoholism comorbidity, we used the alcohol ...