Listar por autor "Ojeda-Pérez, Betsaida"
Mostrando ítems 1-8 de 8
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Brain tissue recovery in obstructive congenital hydrocephalus after intraventricular transplantation of mesenchymal stem cells
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Vitorica Ferrández, Javier; García-Martín, María Luisa; Muñoz, Carmen; Gutiérrez-Pérez, Antonia
; Jiménez-Lara, Antonio Jesús; Páez-González, Patricia[et al.] (2018-10-29)
Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when transplanted. The aim of this study was to ... -
Design of a Stem Cell-Based Therapy for Ependymal Repair in Hydrocephalus Associated With Germinal Matrix Hemorrhages
Rodríguez-Pérez, Luis Manuel; Ojeda-Pérez, Betsaida; López-de-San-Sebastián, Javier; García-Bonilla, María; González-García, Marcos; Fernandez-Muñoz, Beatriz; Sánchez Pernaute, Rosario; García-Martín, María L.; Domínguez-Pinos, Dolores; Cárdenas García, Casimiro; Jiménez-Lara, Antonio Jesús; Páez-González, Patricia[et al.] (AHA/ASA Journals, 2024-04)
BACKGROUND: In preterm birth germinal matrix hemorrhages (GMHs) and the consequent posthemorrhagic hydrocephalus (PHH), the neuroepithelium/ependyma development is disrupted. This work is aimed to explore the possibilities ... -
Generation of periventricular reactive astrocytes overexpressing aquaporin 4 Is stimulated by mesenchymal stem cell therapy
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Rodríguez-Pérez, Luis Manuel; Domínguez-Pinos, Dolores; Vitorica Ferrández, Javier; Jiménez, Sebastián; Ramírez-Lorca, Reposo; Echevarría, Miriam; Cárdenas García, Casimiro; Iglesias, Teresa; Gutiérrez-Pérez, Antonia; McAllister, James P. (II); Limbrick, David D. (Jr.); Páez-González, Patricia; Jiménez-Lara, Antonio Jesús[et al.] (MDPI, 2023-03-15)
Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. Congenital hydrocephalus is associated with a reaction of astrocytes in the periventricular white ... -
Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus
Ojeda-Pérez, Betsaida; Campos-Sandoval, José Ángel; García-Bonilla, María; Cárdenas García, Casimiro; Páez-González, Patricia; Jiménez-Lara, Antonio Jesús[et al.] (BMC, 2021)
Periventricular extracellular oedema, myelin damage, inflammation, and glial reactions are common neuropathological events that occur in the brain in congenital hydrocephalus. The periventricular white matter is the most ... -
Long-time effects of an experimental therapy with mesenchymal stem cells in congenital hydrocephalus
García-Bonilla, María; Ojeda-Pérez, Betsaida; Shumilov, Kirill; Vitorica Ferrández, Javier; Guitérrez, Antonia; Páez-González, Patricia; Jiménez-Lara, Antonio Jesús[et al.] (2019-07-03)
Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when they are transplanted in other neurodegenerative ... -
Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells.
García-Bonilla, María; Ojeda-Pérez, Betsaida; García-Martín, María Luisa; Muñoz-Hernández, María del Carmen; Vitorica Ferrández, Javier; Jiménez, Sebastián; Cifuentes-Rueda, Manuel; Santos-Ruiz, Leonor; Shumilov, Kirill; Claros-Gil, Silvia; Gutiérrez-Pérez, Antonia; Páez-González, Patricia[et al.] (BMC, 2020-03-17)
In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure and the presence of periventricular edema, ischemia/hypoxia, damage of the white matter, and glial ... -
Neuropathological events in an animal model resembling human fetal post-hemorrhagic hydrocephalus
Introduction: In premature newborns, intraventricular hemorrhages (IVH) probably trigger the disruption of the neurogenic ventricular zone. Most of the cases with severe IVH develop post-hemorrhagic hydrocephalus (PHH). ... -
NG2 cells in an animal model of congenital hydrocephalus
Jiménez-Lara, Antonio Jesús; Ojeda-Pérez, Betsaida; García-Bonilla, María; Ruz-Maldonado, Inmaculada; Mateos-Grondona, Jesús; Rodríguez-Pérez, Luis Manuel; Páez-González, Patricia[et al.] (2017-06-28)
NG2 cells are considered oligodendrocyte precursor cells (OPC). In pathological conditions, NG2 cells contribute to generate oligodendrocytes and reactive astrocytes. This study has been designed to uncover the role of NG2 ...