Listar por autor "Bernal, Manuel"
Mostrando ítems 1-5 de 5
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Anti-inflammatory potential of aeroplysinin-1, a bioactive compound isolated from the sponge Aplysina aerophoba
Bravo-Ruiz, Inés; Bernal, Manuel; Manrique-Poyato, Maria Inmaculada; Rodríguez-Quesada, Ana María
; Medina-Torres, Miguel Ángel; Castilla, Laura; Martínez-Póveda, Beatriz Amparo[et al.] (43 Congreso Anual SEBBM, 2021)
Aeroplysinin-1 (Apl-1) is a brominated compound isolated from the marine sponge Aplysina aerophoba that has been shown to possess bioactive effects with a broad spectrum of action in in vitro and in vivo assays. Included ... -
Inhibition of Endothelial Inflammatory Response by HT-C6, a Hydroxytyrosol Alkyl Ether Derivative.
Marrero Capitán, Ana Dácil; Castilla, Laura; Bernal, Manuel; Manrique-Poyato, María Inmaculada; Posligua-García, Joel; Moya-Utrera, Federico; Porras Alcalá, Cristina; Espartero Sánchez, José Luis; Sarabia-García, Francisco Ramón; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (MDPI, 2023-07-28)
Hydroxytyrosol (HT) is a bioactive phenolic compound naturally present in olives and extra virgin olive oil (EVOO) which is described as an antioxidant, antitumoral and antiangiogenic molecule. Previous studies of ... -
Mitochondrial Stress Links Environmental Triggers with Pro-Inflammatory Signaling in Crohn's Disease
(MDPI, 2023)Inflammatory Bowel Diseases (IBD) are a group of chronic, inflammatory disorders of the gut. The incidence and activity of IBD are determined by both genetic and environmental factors. Among these factors, polymorphisms ... -
Study of the antitumor potential of stauprimide in breast cancer
Carrillo Fernández, Paloma; Téllez Quijorna, Clara; Bernal, Manuel; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Martínez-Póveda, Beatriz Amparo[et al.] (2021)
Stauprimide, a semi-synthetic derivative of staurosporine, was characterized in 2009 as a potent differentiation-enhancing compound in embryonic stem cells [1]. Although it was first thought that this compound could maintain ... -
The Extra Virgin Olive Oil phenolic compounds () oleacein and () oleocanthal inhibit tumor cell autophagy
Marrero Capitán, Ana Dácil; Posligua-García, Joel; Bernal, Manuel; Ortega Vidal, Juan; Salido, Sofía; Altarejos, Joaquín; Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel[et al.] (2023)
Our group has recently shown that the antitumor Extra Virgin Olive Oil phenolic compounds (—)oleocanthal and (—)oleacein also behave as antiangiogenic agents. Interestingly, it has been described that phenolic compounds ...