AVISO IMPORTANTE
Recomendamos que se envíen a RIUMA aquellas publicaciones que vayan a utilizar como aportaciones en próximas convocatorias de solicitud de sexenios, solicitud de complementos o acreditación, ya que NO podemos asegurarle que los envíos que se realicen DURANTE EL PERÍODO DE LA CONVOCATORIA, puedan ser aprobados a tiempo.
Listar por autor "Muñoz-Chápuli-Oriol, Ramón"
Mostrando ítems 1-20 de 24
-
Cardiomyocyte-Specific Wt1 Is Involved in Cardiac Metabolism and Response to Damage.
Díaz del Moral, Sandra; Benaouicha, Maha; Villa del Campo, Cristina; Torres, Miguel; Wagner, Nicole; Wagner, Kay-Dietrich; Muñoz-Chápuli-Oriol, Ramón
; Carmona-Mejías, Rita María[et al.] (MDPI, 2023-05-12)
The Wilms tumor suppressor gene (Wt1) encodes a C2H2-type zinc-finger transcription factor that participates in transcriptional regulation, RNA metabolism, and protein–protein interactions. WT1 is involved in the development ... -
Coelomic epithelium-derived cells in visceral morphogenesis
Ariza, Laura; Carmona-Mejías, Rita María; Cañete, Ana; Cano, Elena; Muñoz-Chápuli-Oriol, Ramón (American Association for Anatomy, 2016-03)
Coelomic cavities of vertebrates are lined by a mesothelium which develops from the lateral plate mesoderm. During development, the coelomic epithelium is a highly active cell layer, which locally is able to supply mesenchymal ... -
Deciphering the Involvement of the Epicardium in Cardiac Diseases.
Carmona-Mejías, Rita María; López-Sánchez, Carmen; García-Martínez, Virginio; García-López, Virginio; Muñoz-Chápuli-Oriol, Ramón; Lozano-Velasco, Estefanía; Franco, Diego[et al.] (MDPI, 2023)
The epicardium is a very dynamic cardiac layer with pivotal contributions during cardiogenesis, acting in the postnatal period as an apparently dormant single-cell layer. In mammalian embryos, the epicardium, which ... -
Del conocimiento
Muñoz-Chápuli-Oriol, Ramón (Universidad de Málaga, 2008)
-
Dissecting the role of micro-RNA200B in epicardial-derived cell diversification and migration
Simón Fernández, S; Domínguez, JN; Vilches, JM; Hernández Torres, F; Ramírez Acuña, F; Carmona, R; Guadix-Domínguez, Juan Antonio; Pérez-Pomares, José María; Muñoz-Chápuli-Oriol, Ramón; Franco, D; Aránega, AE[et al.] (2018-11-20)
Mostramos como miR200B se expresa en los estadios E12.5 y E15.5 durante el desarrollo cardiaco, en concreto en una subpoblación de células derivadas del epicardio. Experimentos de pérdida y ganancia de función muestran que ... -
El gen supresor del tumor de Wilms (Wt1) en el desarrollo, homeostasis y regeneración del páncreas
(UMA Editorial, 2020-02-17)Compuesta por cuatro publicaciones que se centran en tres aspectos fundamentales: 1) El papel de las células del epitelio celómico embrionario y por su derivado adulto, el mesotelio. Parece ser que ambos interaccionan con ... -
Expression of the Wilms tumor suppressor gene (Wt1) in a subpopulation of embryonic cardiomyocytes is required for cardiac development
Carmona-Mejías, Rita María; Cañete, Ana; Ariza Medina, Laura Maria; Torrado, Mario; Mikhailov, Alexander; Muñoz-Chápuli-Oriol, Ramón[et al.] (2017-02-06)
The Wilms’ tumour gene, WT1, encodes a zinc-finger transcription factor involved in the development of several organs. WT1 is expressed during mammalian embryonic development in many tissues, including the urogenital system, ... -
Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections
Cano, Elena; Carmona-Mejías, Rita María; Ruiz-Villalba, Adrián; Rojas, Anabel; Chau, You-Ying; Wagner, Kay-Dietrich; Wagner, Nicole; Hastie, Nicholas D.; Muñoz-Chápuli-Oriol, Ramón; Pérez-Pomares, José María[et al.] (Proceedings of the National Academy of Sciences (PNAS), 2016-01)
Recent reports suggest that mammalian embryonic coronary endothelium (CoE) originates from the sinus venosus and ventricular endocardium. However, the contribution of extracardiac cells to CoE is thought to be minor and ... -
Functions of the Wilms' tumor suppressor gene (Wt1) in embryonic and adult myocardium
(UMA Editorial, 2023-06-15)The Wilms’ tumor suppressor gene (Wt1) is expressed in several cell types in the developing and adult heart, including epicardial and endothelial cells, fibroblasts and cardiomyocytes. Systemic Wt1 deletion causes the death ... -
GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice.
Delgado, Irene; Carrasco, Manuel; Cano-Rincón, Elena; Carmona-Mejías, Rita María; García-Carbonero, Rocío; Marín-Gómez, Luis M.; Soria, Bernat; Martín, Francisco; Cano, David A.; Muñoz-Chápuli-Oriol, Ramón; Rojas, Anabel[et al.] (AASLD, 2014-01-10)
The zinc finger transcription factor GATA4 controls specification and differentiation of multiple cell types during embryonic development. In mouse embryonic liver, Gata4 is expressed in the endodermal hepatic bud and in ... -
La expresión miocárdica del gen supresor del tumor de Wilms (Wt1) es esencial para el desarrollo cardíaco y reaparece en cardiomiocitos adultos
Carmona-Mejías, Rita María; Ariza Medina, Laura Maria; Guadix-Domínguez, Juan Antonio; Torrado, Mario; Mikhailov, Alexander; Pérez-Pomares, José María; Muñoz-Chápuli-Oriol, Ramón[et al.] (2017-12-18)
El gen supresor del tumor de Wilms, Wt1, codifica un factor de transcripción del tipo “dedos de zinc” implicado en transcripción, regulación post-transcripcional e interacciones proteína-proteína. La función de este gen ... -
La expresión miocárdica del gen supresor del tumor de Wilms(Wt1) es esencial para el desarrollo cardiaco
Muñoz-Chápuli-Oriol, Ramón; Carmona-Mejías, Rita María; Ariza Medina, Laura Maria; Cañete, Ana; Torrado, Mario; Mikhailov, Alexander; Pérez-Pomares, José María[et al.] (2018-11-09)
El gen supresor del tumor de Wilms,Wt1, codifica un factor de transcripción del tipo “dedos de zinc” implicado en transcripción, regulación post-transcripcional e interacciones proteína-proteína. Durante el desarrollo ... -
Mesothelial-mesenchymal transitions in embryogenesis.
Carmona-Mejías, Rita María; Ariza Medina, Laura Maria; Cano, Elena; Jiménez-Navarro, Manuel Francisco; Muñoz-Chápuli-Oriol, Ramón (Elsevier, 2018)
Most animals develop coelomic cavities lined by an epithelial cell layer called the mesothelium. Embryonic mesothelial cells have the ability to transform into mesenchymal cells which populate many developing organs ... -
Met signaling in cardiomyocytes is required for normal cardiac function in adult mice
Arechedera, María; Carmona-Mejías, Rita María; González-Núñez, María; Gutiérrez-Urquiza, Álvaro; Bragado, Paloma; Cruz-González, Ignacio; Cano, Elena; Guerrero, Carmen; Sánchez, Aránzazu; López-Novao, José Miguel; Schneider, Michael D.; Maina, Flavio; Muñoz-Chápuli-Oriol, Ramón; Porras, Almudena[et al.] (Elsevier, 2013-12)
Hepatocyte growth factor (HGF) and its receptor, Met, are key determinants of distinct developmental processes. Although HGF exerts cardio-protective effects in a number of cardiac pathologies, it remains unknown whether ... -
Molecular evolution of nitric oxide synthases in metazoans.
Muñoz-Chápuli-Oriol, Ramón; González-Doménech, Carmen María (2010-08-09)
Nitric oxide synthases (NOS), the enzymes responsible for the NO synthesis, are present in all eukaryotes. Three isoforms (neuronal, inducible and endothelial), encoded by different loci, have been described in vertebrates, ... -
Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation.
Carmona-Mejías, Rita María; López-Sánchez, Carmen; García-Martínez, Virginio; García-López, Virginio; Muñoz-Chápuli-Oriol, Ramón; Lozano-Velasco, Estefanía; Franco, Diego[et al.] (MDPI, 2023)
The embryonic epicardium originates from the proepicardium, an extracardiac primordium constituted by a cluster of mesothelial cells. In early embryos, the embryonic epicardium is characterized by a squamous cell epithelium ... -
Proteomic data of murine hearts with conditional deletion of the gene Wt1
Díaz del Moral, Sandra; Muñoz-Chápuli-Oriol, Ramón; Carmona-Mejías, Rita María (Universidad de Málaga, 2022-11-10)
Este dataset contiene los resultados de una comparación de la proteómica de corazones de ratones con deleción condicional del gen Wt1 en el miocardio, tratados o no con doxorubicina, y sus correspondientes controles -
Raw data from the paper entitled "Deletion of the Wilms’ tumor suppressor gene in the cardiac troponin-T lineage reveals novel functions of WT1 in heart development"
Muñoz-Chápuli-Oriol, Ramón (Universidad de Málaga, 2021-06-14)
We performed a conditional ablation of Wt1 in the myocardium of mice embryos. RNASeq analysis identified differential expression of 137 genes in the E13.5 mutant heart as compared to controls. We provide raw data about the ... -
The evolutionary origins of chordate hematopoiesis and vertebrate endothelia
Pascual-Anaya, Juan; Albuixech-Crespo, Beatriz; Somorjai, Ildikó M. L.; Carmona-Mejías, Rita María; Oisi, Yasuhiro; Álvarez, Susana; Kuratani, Shigeru; Muñoz-Chápuli-Oriol, Ramón; Garcia-Fernàndez, Jordi[et al.] (Elsevier, 2013-03-15)
The vertebrate circulatory system is the most complex vascular system among those of metazoans, with key innovations including a multi-chambered heart and highly specialized blood cells. Invertebrate vessels, on the other ... -
The proepicardium keeps a potential for glomerular marker expression which supports its evolutionary origin from the pronephros
Cano, Elena; Carmona-Mejías, Rita María; Velecela, Víctor; Martínez-Estrada, Ofelia; Muñoz-Chápuli-Oriol, Ramón (Wiley Online Library, 2015-07)
The proepicardium is the embryonic primordium of the epicardium. This transient structure is essential for cardiac development giving rise to the epicardium and supplying the heart with vascular and cardiac connective ...