Listar por autor "Chaves-Peña, Patricia"
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Acute psychological stress: effects on hippocampal neurogenesis and the role of microglia
Nieto-Quero, Andrea; Chaves-Peña, Patricia; Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Tabbai-Amal, Sara; Muñoz-Martín, José; Pérez-Martín, Margarita
; Pedraza-Benítez, María del Carmen[et al.] (2022)
Among all the factors that can contribute to the onset of psychopathological disorders, stress is the main environmental factor. The hippocampus is one of the most sensitive regions to the harmful effects of stress, in ... -
Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models
Nieto-Quero, Andrea; Chaves-Peña, Patricia; Santín-Núñez, Luis Javier; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen (ELSEVIER, 2021-11)
Stress may have a negative effect on mental health and is the primary environmental risk factor in the aetiology of depression. Nevertheless, the neurobiological mechanisms underlying this mood disorder remain ... -
Effects of chronic stress on hippocampal microglia and neurogenesis of mice under social defeat stress.
Muñoz-Martín, José; Infantes-López, M. Inmaculada; Chaves-Peña, Patricia; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Pedraza-Benítez, María del Carmen; Pérez-Martín, Margarita[et al.] (2022-07)
Introduction: Chronic stress is the main environmental factor in the aetiology of depression and it is known that this type of stress may cause alterations in brain regions such as the hippocampus. Nevertheless, changes ... -
Effects on the hippocampal microglia after acute treatment of a psychological stressor associated with depressive-like behaviours
Nieto-Quero, Andrea; Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Tabbai-Amal, Sara; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen[et al.] (2021-07)
Stressful life events may have a negative impact on mental health compromising people's well-being, so knowing the neurobiological changes that occur after psychosocial stressors can have an impact on overall health. ... -
Female microglia and neurogenesis respond differently to social defeat stress compared to males.
Infantes-López, María Inmaculada; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Nieto-Quero, Andrea; Muñoz-Martín, José; Zea-Doña, Alejandro; Pedraza-Benítez, María del Carmen; Pérez-Martín, Margarita[et al.] (2024)
Depression is a concerning public health threat highly associated with stress. Stress increases brain immune alterations, namely in microglia, which can affect neuron physiology, like neurogenesis, causing a depressive-like ... -
Hippocampal neurogenesis changes in a sex and region-specific manner in adult mice subjected to maternal separation as an early life stress.
Muñoz-Martín, José; Chaves-Peña, Patricia; Infantes-López, María Inmaculada; Zambrana-Infantes, Emma; Nieto-Quero, Andrea; Carayol-Gordillo, Virginia; Martín-Aguiar, Víctor; Zea-Doña, Alejandro; Pedraza-Benítez, María del Carmen; Pérez-Martín, Margarita[et al.] (2024)
Introduction: Early life stress (ELS) might produce long lasting changes in hippocampal neurogenesis and increase the vulnerability to stress-related disorders later in adulthood. Objective: The analysis of immature granule ... -
Microglial and neurogenic alterations in hypothalamus due to acute stress
Infantes-López, M. Inmaculada; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Tabbai-Amal, Sara; Pedraza-Benítez, María del Carmen; Pérez-Martín, Margarita[et al.] (2021-07)
Microglial cells are an important glial population known to be involved in several biological processes such as stress response. These cells engage an activated state following a stress insult that may lead to nervous ... -
Mild juvenile stress increases resilience to the development of anxious behaviors and prevents neurogenic reduction after stress exposure in adulthood.
Chaves-Peña, Patricia; Infantes-López, M. Inmaculada; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Muñoz-Martín, José; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen[et al.] (2023)
Stress, especially during sensitive periods of development, can induce neuroplastic changes in brain regions such as the hippocampus, which increases vulnerability to the negative effects of a second stressor during ... -
Sexual differences in depressive-like behaviours after juvenile and adult stress.
Aguiar-Martín, Victor; Muñoz-Martín, José; Chaves-Peña, Patricia; Infantes-López, M. Inmaculada; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen[et al.] (2024)
Early stress episodes affect brain development and is related to increased risk of developing stress-induced depression in adulthood. However, little is known about the sexual differences in this process. Our goal is to ... -
Sexual differences in hippocampal microglia of adult mice subjected to maternal separation stress.
Muñoz-Martín, José; Infantes-López, M. Inmaculada; Chaves-Peña, Patricia; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Pedraza-Benítez, María del Carmen; Pérez-Martín, Margarita[et al.] (IBRO Congress 2023, 2023)
Introduction: It is well known that early life adversities could a"ect brain development and increase the vulnerability to stress-related disorders later in adulthood. Nevertheless, the neurobiological mechanisms underlying ... -
Social defeat stress induces microglial alterations and impaired cell survival in the hypothalamus according to behavioral phenotype
Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Chaves-Peña, Patricia; Nieto-Quero, Andrea; Muñoz-Martín, José; Pedraza-Benítez, María del Carmen; Pérez-Martín, Margarita[et al.] (2022-07)
Stress is the main environmental cause for depression, known to cause brain immune alterations. As major brain immune cells, microglia undergo transcriptional and, consequently, morphological changes that result in ...