Listar por autor "Nájera-Albendín, Francisco"
Mostrando ítems 1-20 de 30
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Benzotriazole-based multidonor-acceptor systems as attractive two-photon absorption dye platforms
Benítez-Martín, Carlos; Donoso, Beatriz; Torres-Moya, Ivan; Herrera-Imbroda, Jesús; Díaz-Ortiz, Ángel; Nájera-Albendín, Francisco
; Prieto, Pilar; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Elsevier, 2022-02-03)
Pyrazine-decorated benzotriazole cores allow the orthogonal combination of two dipolar systems within a single molecule. A series of this type of derivatives was synthesized and their photophysical features were studied. ... -
Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic
Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Montañe, M I; Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus[et al.] (2013-09-25)
The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ... -
Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications
Benítez-Martín, Carlos; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2018-11-15)
Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in ... -
Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition
Nájera-Albendín, Francisco; Montañez-Vega, María Isabel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Blanca Gómez, Miguel[et al.] (2014-06-12)
Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ... -
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells
Nájera-Albendín, Francisco; Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel (Real Sociedad Española de Química, 2018-06-20)
Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS ... -
Diseño de dendrímeros amino-terminales basados en enlaces tipo amidas. Estructuras con menor repulsión estérica y síntesis a gran escala
Pérez-de-Inestrosa-Villatoro, Ezequiel; Nájera-Albendín, Francisco; Morgado, Anjara; Vida-Pol, Yolanda (2022-05-30)
La estructura ramificada y la elevada multivalencia que presentan los dendrímeros los convierten en excelentes compuestos con potenciales aplicaciones en el campo de la biomedicina. En concreto, los dendrímeros con grupos ... -
Diseño y síntesis de nuevos dendrímeros
Morgado, Anjara; Molina, Noemi; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros son excelentes plataformas multifuncionales para una gran cantidad de diferentes aplicaciones. En particular, el desarrollo de nanoestructuras moleculares multivalentes, con tamaño y forma bien definida, ... -
Diseño y síntesis de nuevos dendrímeros y dendrones. Aplicaciones en regeneración tisular
Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros han generado un enorme interés debido a su particular estructura ramificada y su multivalencia. La extensa investigación que se ha llevado a cabo sobre este tipo de macromoléculas ha demostrado la naturaleza ... -
Diseño y síntesis de nuevos dendrones para aplicaciones biomédicas
Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros han sido empleados en una gran variedad de aplicaciones, entre las que destacan las del campo de la biomedicina. Estas macromoléculas multivalentes ofrecen la posibilidad de incorporar múltiples funcionalidades ... -
Energy transfer in Aminonaphthalimide-BODIPY dyads upon one and two photons excitation
Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2014-07-03)
BODIPY dyes are nowadays widely commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry [1]. However, the generally very small Stokes shifts of BODIPY dyes may cause ... -
Fijación de dendrímeros antigénicos en superficies para determinación de IgE
Vida-Pol, Yolanda; Montañez-Vega, María Isabel; Mesa, Pablo; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2016-02-15)
Actualmente, el diseño de nuevos materiales con potenciales aplicaciones biomédicas es de gran importancia , sobre todo para su uso directo en diagnóstico clínico . En particular, los dispositivos que ... -
Influencia de la Atropoisomería en la Organización Helicoidal de Organogeles en oligo-p-fenilenos
Nieto-Ortega, Belén; Aparicio, Fátima; Nájera-Albendín, Francisco; Ramírez-Aguilar, Francisco Javier; López-Navarrete, Juan Teodomiro; Casado-Cordón, Juan; Sánchez, Luis[et al.] (Real Sociedad Española de Quimica, 2013-09-04)
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Managing with (fluorescent)-biomimetic dendrimers
Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Mesa-Antunez, Pablo; Ruiz-Sanchez, Antonio Jesus; Molina, Noemi; Morgado, Anjara[et al.] (2017-06-30)
Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes. Diagnosis via specific interactions with target proteins is one of the objectives that has been given more ... -
NanoFN10: A High-Contrast Turn-On Fluorescence Nanoprobe for Multiphoton Singlet Oxygen Imaging.
Zanocco, Renzo P.; Nájera-Albendín, Francisco; Pérez-Inestrosa, Ezequiel; Zanocco, Antonio L.; Lemp, Else; Nonell-Marrugat, Santiago[et al.] (MDPI, 2023-05-09)
An “off-on” fluorescent nanoprobe for near-infrared multiphoton imaging of singlet oxygen has been developed. The nanoprobe comprises a naphthoxazole fluorescent unit and a singlet-oxygen-sensitive furan derivative attached ... -
New indolium fluorofores for two-photon absortion (2PA) bioimaging applications
The development of organic materials with 2PA has attracted intensive attention in the past two decades [1]. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section (σ2PA) ... -
New molecules based indolium for two-photon absortion bioimaging applications
Benítez-Martín, Carlos; Pérez-de-Inestrosa-Villatoro, Ezequiel; Nájera-Albendín, Francisco (Universidad de Extremadura, 2017)
The development of organic materials with 2PA has attracted intensive attention in the past two decades. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section and good ... -
Novel probes for simultaneous dual-colour labelling of mitochondria and lysosomes.
Cellular activity depends on the accurately controlled and synchronised functions of the subcellular organelle ensemble. In this context, lysosomes and mitochondria are central to cellular metabolism as major contributors ... -
“Off-on” two-photon indolenine probes for pH bioimaging
Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pearson, John R.; Nájera-Albendín, Francisco; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2019-10-25)
Fluorescence-based biosensors have become an indispensable tool in modern biology. These molecules can be used to monitor processes inside living cells and in real-time. The control of the pH is crucial in multiple biological ... -
Preparation, photophysical properties and cell image of Naphthalimide-based fluorescent nanostructures for biomedical applications: BAPAD dendrimeric antigens and silica nanoparticles
Mesa, Pablo; Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2014-07-17)
We present here the synthesis and characterization of BAPAD [1] fluorescent Dendrimeric-Antigens (DeAn), to be applied in basophil activation as a test to detect drug allergy reactions. A second generation BAPAD dendrimer ... -
RGD peptide on Dendrimer surfaces Affects Mesenchymal Stem Cells Adhesion
Vida-Pol, Yolanda; Molina, Noemi; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Lagunas, Anna; Claros-Gil, Silvia; Becerra-Ratia, José; Andrades-Gómez, José Antonio; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2016-04-07)
Mesenchymal stem cells (MSCs) are promising candidates for a range of tissue regeneration applications. Adequate scaffolds are necessary for their application in vivo, where interactions between cells and the surface ...