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Listar por autor "Pérez-de-Inestrosa-Villatoro, Ezequiel"
Mostrando ítems 1-20 de 52
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Aminonaphthalimide-squaraine dyads: photophysical properties and bioimaging application
Squaraines is an important part of the cyanine family which have high extinction coefficients, sharp absorption bands, and intense fluorescence spectra in the red and near infrared region in solution.[1] The unique electronic ... -
Behavior of osteoprogenitor cells on EBM-sintered Ti6Al4V-scaffolds coated RGD-presenting hemidendrons. Implications for prosthesis design
González, Ana; Cabeza, Noemí; Vida-Pol, Yolanda
; Pérez-de-Inestrosa-Villatoro, Ezequiel; Santos-Ruiz, Leonor; Becerra-Ratia, José; Monopoli, Donato[et al.] (2017-12-12)
Titanium-based prosthetic implants are commonly used in Traumatology and Maxillofacial Surgery to achieve functional recovery of a severely damaged bones. Prosthetic replacements fail in the long term due to poor ... -
Benzotriazole-based multidonor-acceptor systems as attractive two-photon absorption dye platforms
Benítez-Martín, Carlos; Donoso, Beatriz; Torres-Moya, Ivan; Herrera-Imbroda, Jesús; Díaz-Ortiz, Ángel; Nájera-Albendín, Francisco; Prieto, Pilar; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Elsevier, 2022-02-03)
Pyrazine-decorated benzotriazole cores allow the orthogonal combination of two dipolar systems within a single molecule. A series of this type of derivatives was synthesized and their photophysical features were studied. ... -
Cation template assisted oligoethylene glycol desymmetrization by intramolecular Cannizzaro reaction of topologically remote aldehydes.
Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Suau Suárez, Rafael; Pérez-de-Inestrosa-Villatoro, Ezequiel (Elsevier, 2008)
Oligoethylene glycol chains containing 2–5 ethylene glycol units, and possessing a benzyl alcohol and a benzoic acid end groups, can be quantitatively obtained by intramolecular Cannizzaro reaction of the corresponding ... -
Dendrimer-Modified Solid Supports: Nanostructured Materials with Potential Drug Allergy Diagnostic Applications
Ruiz-Sanchez, Antonio Jesus; Montañez-Vega, María Isabel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel (CURRENT MEDICINAL CHEMISTRY, 2012)
Complex functional materials consisting of bioactive molecules immobilized on solid supports present potential applications in biosensoring. Advances in the fabrication of these surface materials are of growing interest ... -
Dendrimeric Antigens. New Approaches Towards Detection of IgE‐Mediated Drug Allergy Reactions
Montañez-Vega, María Isabel; Mayorga, Cristobalina; Torres-Jaén, María Josefa; Ruiz-Sánchez, Antonio Jesús; Malkoch, M; Hult, A; Blanca, Miguel; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (RSC Publishing, 2013-05-31)
Drugs are low molecular weight substances which cannot cause an immune response on their own. However, they can act as haptens and form covalent adducts with proteins. The resulting hapten‐carrier (drug‐protein) conjugate ... -
Dendrímeros Antigénicos fijados sobre nanopartículas para diagnostico in vitro de alergia a fármacos
(UMA Editorial, 2022-07-18)Las Reacciones Adversas a Fármacos (RAF) constituyen actualmente un problema sanitario importante debido al gran desconocimiento sobre los mecanismos por los que se desencadenan, lo que se traduce en una ausencia de pruebas ... -
Dendrímeros antigénicos sobre partículas de sílica para determinar IgE específicas de antibióticos betalactámicos
Matamoros Castellano, Esther; Jiménez, Isabel M.; Gil-Ocaña, Violeta; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Céspedes Lagos, José Antonio; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Cazorla, María Isabel[et al.] (2022)
Los inmunoensayos empleados para el diagnóstico in vitro de alergias a antibióticos betalactámicos actualmente presentan una limitada sensibilidad y pobre especificidad, además de no estar disponibles de forma comercial ... -
Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic
Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Montañe, M I; Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus[et al.] (2013-09-25)
The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ... -
Design and synthesis of new dendrons for biomedical applications
Dendrons are excellent multifunctional platforms for many different applications. In particular, the development of multivalent molecular nanostructures, with a well-defined size and shape, has an enormous interest in the ... -
Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications
Benítez-Martín, Carlos; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2018-11-15)
Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in ... -
Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition
Nájera-Albendín, Francisco; Montañez-Vega, María Isabel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Blanca Gómez, Miguel[et al.] (2014-06-12)
Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ... -
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells
Nájera-Albendín, Francisco; Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel (Real Sociedad Española de Química, 2018-06-20)
Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS ... -
Development of Novel Nanobiosensors for Diagnostics of Adverse Drug Reactions.
(UMA Editorial, 2023)Amoxicilina es uno de los antibioticos del grupo de penicilinas más usados. Penicilinas son el grupo de antibioticos que provocan más reaciones alérgicas entre todos los medicamentos. Diagnóstico correcto es necesario para ... -
Direct characterization of functional materials by haptenized fluorescent dendrimers for in vitro allergic drug diagnose
Ruiz-Sanchez, Antonio Jesus; Collado-Martín, Daniel; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Pérez-de-Inestrosa-Villatoro, Ezequiel (2020-10-01)
β-lactams are the most widely drug prescribed against infections, but they are the most commonly reported medication allergy too. A correct diagnosis of these allergic reactions is crucial to avoid rejecting them by other ... -
Diseño de dendrímeros amino-terminales basados en enlaces tipo amidas. Estructuras con menor repulsión estérica y síntesis a gran escala
Pérez-de-Inestrosa-Villatoro, Ezequiel; Nájera-Albendín, Francisco; Morgado, Anjara; Vida-Pol, Yolanda (2022-05-30)
La estructura ramificada y la elevada multivalencia que presentan los dendrímeros los convierten en excelentes compuestos con potenciales aplicaciones en el campo de la biomedicina. En concreto, los dendrímeros con grupos ... -
Diseño y síntesis de nuevos dendrímeros
Morgado, Anjara; Molina, Noemi; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros son excelentes plataformas multifuncionales para una gran cantidad de diferentes aplicaciones. En particular, el desarrollo de nanoestructuras moleculares multivalentes, con tamaño y forma bien definida, ... -
Diseño y síntesis de nuevos dendrímeros y dendrones. Aplicaciones en regeneración tisular
Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros han generado un enorme interés debido a su particular estructura ramificada y su multivalencia. La extensa investigación que se ha llevado a cabo sobre este tipo de macromoléculas ha demostrado la naturaleza ... -
Diseño y síntesis de nuevos dendrones para aplicaciones biomédicas
Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)
Los dendrímeros han sido empleados en una gran variedad de aplicaciones, entre las que destacan las del campo de la biomedicina. Estas macromoléculas multivalentes ofrecen la posibilidad de incorporar múltiples funcionalidades ... -
Energy transfer in Aminonaphthalimide-BODIPY dyads upon one and two photons excitation
Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2014-07-03)
BODIPY dyes are nowadays widely commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry [1]. However, the generally very small Stokes shifts of BODIPY dyes may cause ...