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Listar por autor "Becerra-Ratia, Jose"
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A model of maxilla resection to test new hybrid implants:macroporous titanium and tissue engineering elements
Santos-Ruiz, L; Monopoli, D; Yañez, Jl; Mentado, B; Ruiz, F; [et al.] (2015-07-23)Maxillary bone loss in commonly found in humans, due to bone ageing, tooth loos, periodontal disease and, more severely, to trauma, radiotherapy and tumor resection. Masillofacial reconstructive surgery is a still unmet ... -
A synthetic collagen-binding arg-gly-asp (rgd) biomimetic peptide enhances bone cell differentiation
Visser, Rick; Arrabal, Pilar M.; Santos-Ruiz, Leonor; Fernández-Barranco, Raúl; Cifuentes, Manuel; [et al.] (2013-11-27)RGD (arginine-glycine-aspartic acid) peptides have shown some promising abilities to promote the attachment of cells to biomaterials and to direct their differentiation. However, anchoring these peptides to the biomaterial’s ... -
Behavior of osteoprogenitor cells on EBM-sintered Ti6Al4V-scaffolds coated RGD-presenting hemidendrons. Implications for prosthesis design
González, Ana; Cabeza, Noemí; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel; Santos-Ruiz, Leonor; [et al.] (2017-12-12)Titanium-based prosthetic implants are commonly used in Traumatology and Maxillofacial Surgery to achieve functional recovery of a severely damaged bones. Prosthetic replacements fail in the long term due to poor ... -
Bone marrow mesenchymal stem cells, collagen scaffold and BMP-2 for rat spinal fusio
Arrabal, Pilar M.; Visser, R.; Cifuentes, Manuel; Becerra-Ratia, Jose; Jiménez-Enjuto, E. (2013-11-08)The use of autograft for posterolateral spinal fusion, continue being considered the gold standard for the treatment of spine pathologies. However, due to complications such as donor site morbidity, increased operating ... -
Combining tissue engineering with metal scaffolds in orthopaedic to improve osseointegration of endoprothesis
Amat Trujillo, Daniel; Becerra-Ratia, Jose; Santos Ruiz, L.; Belmonte, R. (2013-11-08)Electron Beam Melting (EBM) technology allows the fabrication of free-formed metal scaffolds, thus creating the possibility of manufacturing patient-specific endo-prostheses. It also allows the production of highly-porous ... -
Desarrollo de prototipos de soportes tridimensionales a base de colágeno tipo I e hidroxiapatita para regeneración ósea
Moncayo Donoso, Miguel Ángel (UMA Editorial, 2022)El hueso es uno de los tejidos de mayor demanda para trasplante a nivel mundial, representando cerca de 2,2 millones de injertos anualmente. Por medio de la ingeniería de tejidos ósea (BTE) se han desarrollado estrategias ... -
Diseño de nuevas estrategias moleculares para la funcionalización de colágeno tipo I en ingeniería tisular ósea
Rico-Llanos, Gustavo Adolfo (UMA Editorial, 2018)El colágeno tipo I, funcionalizado con proteína morfogenética de hueso 2 (BMP-2), es un biomaterial ampliamente utilizado en ingeniería tisular y cirugía ortopédica como alternativa al implante de hueso autólogo en los ... -
En memoria de Cajal
Becerra-Ratia, Jose (Universidad de Málaga, 2006) -
IGF-1 enhances the osteogenic activity of BMP-6 in vitro and in vivo
Rico-Llanos, Gustavo Adolfo; Becerra-Ratia, Jose; Visser, Rick (2017-10-25)Bone morphogenetic protein-2 (BMP-2) is widely used in orthopedic surgery and bone tissue engineering because of its strong osteogenic activity. However, BMP-2 treatments have several drawbacks and alternatives are being ... -
IGF-1 enhances the osteogenic activity of BMP-6 in vitro and in vivo, and together have a stronger osteogenic effect than when IGF-1 is combined with BMP-2
Rico-Llanos, Gustavo; Becerra-Ratia, Jose; Visser, Rick (2017-11-24)Bone morphogenetic protein-2 (BMP-2) is widely used in orthopedic surgery and bone tissue engineering because of its strong osteogenic activity. However, BMP-2 treatments have several drawbacks and alternatives are being ... -
On the potential of decidua-derived MSC as therapeutic agents for bone repair
Belmonte, Rosa María; Flores, Ana Isabel; Amat Trujillo, Daniel; González-Luque, Ana; Becerra-Ratia, Jose; [et al.] (2016-10-25)OBJECTIVE: Adult mesenchymal stem cells derived from fat or bone marrow represent a promising therapeutic treatment to promote tissue regeneration. However, their availability is limited by the number of donors who are ... -
RGD peptide on Dendrimer surfaces Affects Mesenchymal Stem Cells Adhesion
Vida-Pol, Yolanda; Molina, Noemi; Collado, Daniel; Najera-Albendin, Francisco; Lagunas, Anna; [et al.] (2016-04-07)Mesenchymal stem cells (MSCs) are promising candidates for a range of tissue regeneration applications. Adequate scaffolds are necessary for their application in vivo, where interactions between cells and the surface ... -
RGD-dendritic structures on titanium alloy. Influence in the relationship between bone cells and the metal surface
Molina, Noemí; González-Luque, Ana; Becerra-Ratia, Jose; Santos-Ruiz, Leonor; Vida-Pol, Yolanda; [et al.] (2019-09-18)Prosthetic implants are used in surgical procedures to replace a joint (hip or knee) allowing the functional recovery of the patient. Prostheses are usually made of titanium alloys. However, the lack of chemical and ... -
Secretory Profile of Adipose-Tissue-Derived Mesenchymal Stem Cells from Cats with Calicivirus-Positive Severe Chronic Gingivostomatitis
Villatoro, Antonio J.; Martín Astorga, María del Carmen; Alcoholado Cueto, Cristina; Kazantseva, Liliya; Cardenas, Casimiro; [et al.] (IOAP-MPDI, 2022-05-25)The feline calicivirus (FCV) causes infections in cats all over the world and seems to be related to a broad variety of clinical presentations, such as feline chronic gingivostomatitis (FCGS), a severe oral pathology in ... -
Tenocytic induction of stem cells from bone marrow on polymeric microparticles for a new concept of tendon regenerative prosthesis
Claros, Silvia; Araque-Monrós, Mª Carmen; Rodríguez-Losada, Noela; Gil-Santos, Luis; Monleón-Pradas, Manuel; [et al.] (2015-10-26)A new concept of a regenerative and resorbable prosthesis for tendon and ligament has been developed. The prosthesis consists of a poly-lactide acid (PLA) braid, microparticles in its interior serving as cell carriers, and ... -
The effect of combining bone morphogenetic proteins -2 and -6 on osteoblastic differentiation and bone
Rico-Llanos, Gustavo; Bodnárová, Kristina; Arrabal, Pilar M.; Cifuentes, Manuel; Becerra-Ratia, Jose (2015-07-21)Bone morphogenetic proteins-2 and -7 (BMP-2 and -7) are the only two members of the BMP subfamily approved to date to be used in combination with collagen type I in orthopedic surgery, although other BMPs have proven to ...