Listar por autor "Béjar-Alvarado, Julia"
Mostrando ítems 1-20 de 45
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Actividad antagonista de aislados del Virus de la Septicemia Hemorrágica Viral (VHSV) frente al sistema del interferón tipo I de lenguado senegalés
Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther
; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (2017-10-11)
Senegalese sole (Solea senegalensis) is susceptible to marine Viral Haemorrhagic Septicaemia Virus (VHSV) isolates, but it is not affected by freshwater VHSV isolates. In addition, the sole type I interferon (IFN I) response ... -
Actividad inmunomoduladora y antiviral del Propil Propano Tiosulfinato, un compuesto derivado de la cebolla, frente a betanodavirus
Moreno, Patricia; Baños-Arjona, Alberto; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Béjar-Alvarado, Julia (2022-11)
Los compuestos organosulfurados de las especies del género Allium, como el PropilPropano Tiosulfinato (PTS), se utilizan como aditivos funcionales en alimentación animal por sus propiedades antimicrobianas. Sin embargo, ... -
Antiviral activity of mx proteins from gilthead seabream (sparus aurata) against lymphocystis disease virus (LCDV).
Fernández-Trujillo, M. Alejandra; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (ELSEVIER, 2013)
Gilthead seabream (Sparus aurata), one of the most important fish species in the Mediterranean Aquaculture displays a high natural resistance to viral diseases. Until now, the main viral disease affecting gilthead seabream ... -
Anti‑nervous necrosis virus activity of the growth hormone releasing peptide‑6, GHRP‑6
Álvarez-Torres, Daniel; Martínez, Rebeca; Moreno, Patricia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Porras Estrada, Mario; Béjar-Alvarado, Julia[et al.] (Springer Nature, 2025-04-30)
Growth hormone-releasing peptide 6 (GHRP-6), is a six-amino acid synthetic peptide that acts as a ghrelin analog and has shown growth-promoting and immunomodulatory activities in several fish species. This study evaluates ... -
Betanodavirus Quantification and IFN I-Antagonism Detection Using Luciferase Reporter Systems Based on Fish mx Promoters
Álvarez-Torres, Daniel; Moreno, Patricia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (Wiley, 2025-06-12)
Mx genes display strong and quick induction in response to viral infections, which varies according to the viral virulence; furthermore, mx transcription is blocked by several viruses as part of their immune evasion ... -
Caracterización de los promotores de las proteínas antivirales Mx1, Mx2 y Mx3 de dorada (Sparus aurata)
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)La dorada es una especie de gran interés para la Acuicultura del Sur de Europa. Las notables pérdidas en la acuicultura moderna debidas a patologías de distinta índole, han suscitado entre los científicos la necesidad de ... -
Characterization of Senegalese sole (Solea senegalensis) Mx promoter
Carballo Perez, Carlos; Alonso-Sánchez, María del Carmen; Collet, Bertrand; Béjar-Alvarado, Julia; Álvarez-Torres, Daniel; García-Rosado, Esther[et al.] (Elsevier, 2013)
Type I interferon (IFN) represents a first component of the innate immune response against viral infections, promoting an antiviral state in cells. Mx proteins are the best studied IFN-inducible genes (ISGs) in fish. The ... -
Combined dietary administration of Chlorella fusca and ethanol-inactivated Vibrio proteolyticus modulates intestinal microbiota and gene expression in Chelon labrosus
García-Márquez, Jorge; Álvarez-Torres, Daniel; Cerezo Ortega, Isabel M.; Domínguez-Maqueda, Marta; López-Figueroa, Félix; Alarcón, Francisco Javier; Acién-Fernández, Francisco Gabriel; Martínez-Manzanares, Eduardo; Abdala-Díaz, Roberto Teófilo; Béjar-Alvarado, Julia; Arijo-Andrade, Salvador[et al.] (MDPI, 2023-10)
The use of functional feeds in aquaculture is currently increasing. This study aimed to assess the combined impact of dietary green microalgae Chlorella fusca and ethanol-inactivated Vibrio proteolyticus DCF12.2 (CVP diet) ... -
Cytokine-like activity of European sea bass ISG15 protein on RGNNV-infected E−11 cells
Moreno García, Patricia; Leiva Rebollo, Rocío; García Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen (Elsevier, 2022-08-18)
IFN-I generates an antiviral state by inducing the expression of numerous genes, called IFN-stimulated genes, ISGs, including ISG15, which is the only ISG with cytokine-like activity. In a previous study, we developed ... -
Cytokine-like activity of European sea bass ISG15 protein on RGNNV-infected E−11 cells
Moreno-García, Patricia; Leiva-Rebollo, Rocío; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen (Elsevier, 2022-08-23)
IFN-I generates an antiviral state by inducing the expression of numerous genes, called IFN-stimulated genes, ISGs, including ISG15, which is the only ISG with cytokine-like activity. In a previous study, we developed ... -
Development of in vitro systems to study IFN signalling in gilthead seabream (Sparus aurata)
González-Mariscal, J.A.; Fernández-Trujillo, M. Alejandra; Méndez, T.; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-12-11)
Type I interferon (IFN I) triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. In contrats, type II IFN (IFN II) is generally accepted to be ... -
Differences in the viral induction of the senegalese sole Mx protein in RTG-2 and CHSE-214 cells
Álvarez-Torres, Daniel; Podadera, Ana Maria; García-Rosado, Esther; Collet, Bertrand; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (EAFP, 2013)
Transfected RTG-2 cells infected with VHSV showed significant induction of the luciferase reporter gene, compared to the control non-infected cells, at 24, 48 and 72 h post infection (p.i.). The maximum expression was ... -
Differential antiviral activity of Porphyridium cruentum polysaccharides against VHSV and NNV infections
Parra-Riofrio, Geovanna; Moreno-García, Patricia; Abdala-Díaz, Roberto Teófilo; García-Rosado, Esther; Uribe-Tapia, Eduardo; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia[et al.] (2021-09)
The use of functional food can be an interesting approach to prevent viral diseases in aquaculture facilities. An increasing number of studies have suggested that marine microorganisms can be a relevant source of substances ... -
Differential immunogene expression profile of European sea bass (Dicentrarchus labrax, L.) in response to highly and low virulent NN
Moreno, Patricia; Gémez-Mata, Juan; García-Rosado, Esther; Béjar-Alvarado, Julia; Labella Vera, Alejandro Manuel; Souto, Sandra; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2020)
European sea bass is highly susceptible to the nervous necrosis virus, RGNNV genotype, whereas natural outbreaks caused by the SJNNV genotype have not been recorded. The onset and severity of an infectious disease depend ... -
Differential induction of the gilthead seabream Mx1, Mx2 and Mx3 promoters by IPNV and VHSV
González-Mariscal, J.A.; Fernández-Trujillo, M. Alejandra; Méndez, T.; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-10-07)
Type I interferon (IFN I) system triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. The complex expression regulation of Interferon Stimulated ... -
Las dos proteínas Mx de lubina (Dicentrarchus labrax) responden de forma diferente a la infección por VNNV
Novel, Patricia; Fernández-Trujillo, M. Alejandra; Manchado, Manuel; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia (2013-10-01)
Las proteínas Mx son elementos clave en el estado antiviral desencadenado por el interferón tipo I en respuesta a las infecciones virales. En este trabajo se han identificado dos genes Mx en lubina (Dicentrarchus labrax), ... -
Efecto de la inclusión de Chlorella fusca en la dieta de lisas cultivadas (Chelon labrosus) sobre la expresión génica y a la microbiota de los peces
García-Márquez, Jorge; Álvarez-Torres, Daniel; Cerezo Ortega, Isabel M.; Domínguez-Maqueda, Marta; López-Figueroa, Félix; Martínez-Manzanares, Eduardo; Abdala-Díaz, Roberto Teófilo; Béjar-Alvarado, Julia; Arijo-Andrade, Salvador[et al.] (2022)
Este trabajo tuvo como objetivo evaluar los efectos de la inclusión de la microalga Chlorella fusca sobre la microbiota intestinal y la expresión génica en juveniles de Chelon labrosus. Los peces fueron alimentados con una ... -
Estudio in vitro de la actividad antagonista de aislados del virus de la septicemia hemorrágica viral (VHSV) de distinto origen sobre el sistema del IFN tipo I
Gémez-Mata, Juan; Álvarez-Torres, Daniel; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Béjar-Alvarado, Julia (2018-11-09)
El lenguado senegalés (Solea senegalensis) es susceptible a aislados marinos del virus de la septicemia hemorrágica viral (VHSV); sin embargo, los VHSV patógenos para especies de agua dulce no son virulentos para especies ... -
Estudio in vitro de la actividad tipo citoquina de ISG15 de lubina frente a infecciones por Betanodavirus
Moreno-García, Patricia; Leiva-Rebollo, Rocío; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen (2022-09)
El sistema interferón tipo I (IFN-I) establece un estado antiviral mediante la transcripción de los llamados genes estimulados por IFN (ISG). Destaca el gen isg15, cuya proteína es la única descrita que presenta actividad ... -
European sea bass RTP3 genes: genomic characterization and transcription analyses.
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2023)
Introduction: Fish RTP3, belonging to receptor-transporting protein (RTP) family, has been described as an interferon-α (IFN-α)-responsive gene. However, little information is available about fish rtp3 gene structure and ...