Listar por autor "Serrano-Garballo, Alfonso"
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Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity
Redondo-Bautista, Maximino
; Téllez-Santana, Teresa; Roldán Cardenete, María José; Serrano-Garballo, Alfonso; García Aranda, Marilina; Gleave, Martin E; Hortas Nieto, María Luisa; Morell Ocaña, Miguel[et al.] (BMC Springer Nature, 2007-12-13)
Introduction: Overexpression of the apoptosis-related protein clusterin is associated with breast cancer development and tumor progression. We describe the use of clusterin-specific antisense oligonucleotides and antibodies ... -
Downregulation of clusterin mediates sensitivity to protein kinase inhibitors in breast cancer cells.
Redondo-Bautista, Maximino; García Aranda, Marilina; Roldán Cardenete, María José; Callejón, Gonzalo; Serrano-Garballo, Alfonso; Jimenez, Eugenio; Téllez-Santana, Teresa[et al.] (Lipincott, 2015)
The efficacy of protein kinase inhibitors (PKIs) has been shown in clinical assays for cancer, but as isolated agents, they only have a modest effect. One of the most important characteristics of mitogen-activated PKIs is ...