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Listar por autor "Vida-Pol, Yolanda"
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Amoxicillin Haptenation of Alpha-Enolase is Modulated by Active Site Occupancy and Acetylation.
Vida-Pol, Yolanda; Pérez-Inestrosa, Ezequiel; González Morena, Juan Manuel; Sanchez Gomez, Francisco J; Salas, María; Montañez-Vega, María Isabel; Altomare, Alessandra; Aldini, Giancarlo; Pajares, Maria Angeles; Pérez-Sala, Dolores[et al.] (Frontiers, 2022)Allergic reactions to antibiotics are a major concern in the clinic. ß-lactam antibiotics are the class most frequently reported to cause hypersensitivity reactions. One of the mechanisms involved in this outcome is the ... -
Behavior of osteoprogenitor cells on EBM-sintered Ti6Al4V-scaffolds coated RGD-presenting hemidendrons. Implications for prosthesis design
González, Ana; Cabeza, Noemí; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Santos-Ruiz, Leonor; Becerra-Ratia, José; Monopoli, Donato[et al.] (2017-12-12)Titanium-based prosthetic implants are commonly used in Traumatology and Maxillofacial Surgery to achieve functional recovery of a severely damaged bones. Prosthetic replacements fail in the long term due to poor ... -
Cation template assisted oligoethylene glycol desymmetrization by intramolecular Cannizzaro reaction of topologically remote aldehydes.
Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Suau Suárez, Rafael; Pérez-de-Inestrosa-Villatoro, Ezequiel (Elsevier, 2008)Oligoethylene glycol chains containing 2–5 ethylene glycol units, and possessing a benzyl alcohol and a benzoic acid end groups, can be quantitatively obtained by intramolecular Cannizzaro reaction of the corresponding ... -
Dendrimer surface orientation of the RGD peptide affects mesenchymal stem cell adhesion.
Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Claros-Gil, Silvia; Becerra-Ratia, José; Andrades-Gómez, José Antonio; Pérez-Inestrosa, Ezequiel[et al.] (Royal Society of Chemistry, 2016-05-17)Mesenchymal stem cells (MSCs) are promising candidates for a range of tissue regeneration applications. Adequate scaffolds are necessary for their application in vivo, where interactions between cells and the surface ... -
Dendrimer-Modified Solid Supports: Nanostructured Materials with Potential Drug Allergy Diagnostic Applications
Ruiz-Sanchez, Antonio Jesus; Montañez-Vega, María Isabel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel (CURRENT MEDICINAL CHEMISTRY, 2012)Complex functional materials consisting of bioactive molecules immobilized on solid supports present potential applications in biosensoring. Advances in the fabrication of these surface materials are of growing interest ... -
Dendrímeros Antigénicos fijados sobre nanopartículas para diagnostico in vitro de alergia a fármacos
Gil Ocaña, Violeta Isabel (UMA Editorial, 2022-07-18)Las Reacciones Adversas a Fármacos (RAF) constituyen actualmente un problema sanitario importante debido al gran desconocimiento sobre los mecanismos por los que se desencadenan, lo que se traduce en una ausencia de pruebas ... -
Dendrímeros antigénicos sobre partículas de sílica para determinar IgE específicas de antibióticos betalactámicos
Matamoros Castellano, Esther; Jiménez, Isabel M.; Gil-Ocaña, Violeta; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Céspedes Lagos, José Antonio; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Cazorla, María Isabel[et al.] (2022)Los inmunoensayos empleados para el diagnóstico in vitro de alergias a antibióticos betalactámicos actualmente presentan una limitada sensibilidad y pobre especificidad, además de no estar disponibles de forma comercial ... -
Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic
Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Montañe, M I; Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus[et al.] (2013-09-25)The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ... -
Dendritic scaffold onto titanium implants. A versatile strategy increasing biocompatibility.
Molina, Noemí; González, Ana; Monopoli, Donato; Mentado, Belinda; Becerra-Ratia, José; Santos-Ruiz, Leonor; Vida-Pol, Yolanda; Pérez-Inestrosa, Ezequiel[et al.] (MDPI, 2020-04-01)Osseointegration of metal prosthetic implants is a yet unresolved clinical need that depends on the interplay between the implant surface and bone cells. The lack of a relationship between bone cells and metal has traditionally ... -
Design and synthesis of new dendrons for biomedical applications
Dendrons are excellent multifunctional platforms for many different applications. In particular, the development of multivalent molecular nanostructures, with a well-defined size and shape, has an enormous interest in the ... -
Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition
Nájera-Albendín, Francisco; Montañez-Vega, María Isabel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Blanca Gómez, Miguel[et al.] (2014-06-12)Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ... -
Diseño de dendrímeros amino-terminales basados en enlaces tipo amidas. Estructuras con menor repulsión estérica y síntesis a gran escala
Pérez-de-Inestrosa-Villatoro, Ezequiel; Nájera-Albendín, Francisco; Morgado, Anjara; Vida-Pol, Yolanda (2022-05-30)La estructura ramificada y la elevada multivalencia que presentan los dendrímeros los convierten en excelentes compuestos con potenciales aplicaciones en el campo de la biomedicina. En concreto, los dendrímeros con grupos ... -
Diseño y síntesis de nuevos dendrímeros
Morgado, Anjara; Molina, Noemi; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)Los dendrímeros son excelentes plataformas multifuncionales para una gran cantidad de diferentes aplicaciones. En particular, el desarrollo de nanoestructuras moleculares multivalentes, con tamaño y forma bien definida, ... -
Diseño y síntesis de nuevos dendrímeros y dendrones. Aplicaciones en regeneración tisular
Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)Los dendrímeros han generado un enorme interés debido a su particular estructura ramificada y su multivalencia. La extensa investigación que se ha llevado a cabo sobre este tipo de macromoléculas ha demostrado la naturaleza ... -
Diseño y síntesis de nuevos dendrones para aplicaciones biomédicas
Molina, Noemi; Morgado, Anjara; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2018-03-06)Los dendrímeros han sido empleados en una gran variedad de aplicaciones, entre las que destacan las del campo de la biomedicina. Estas macromoléculas multivalentes ofrecen la posibilidad de incorporar múltiples funcionalidades ... -
Dynamic Covalent Properties of a Novel Indolo[3,2-b]carbazole Diradical
Badía-Domínguez, Irene; Peña-Álvarez, Miriam; Wang, Deliang; Pérez Guardiola, Andrés; Vida-Pol, Yolanda; Rodríguez-González, Sandra; López Navarrete, Juan T.; Hernández-Jolín, Víctor; Sancho-García, Juan C.; García-Baonza, Valentín; Nash, Rosie; Hartl, František; Li, Hongxiang; Ruiz-Delgado, María del Carmen[et al.] (Wiley, 2021)This work describes the synthesis and properties of a dicyanomethylene-substituted indolo[3,2-b]carbazole diradical ICz-CN. This quinoidal system dimerises almost completely to (ICz-CN)2, which contains two long C(sp3)−C(sp3) ... -
Energy transfer in Aminonaphthalimide-BODIPY dyads upon one and two photons excitation
Collado-Martín, Daniel; Vida-Pol, Yolanda; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2014-07-03)BODIPY dyes are nowadays widely commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry [1]. However, the generally very small Stokes shifts of BODIPY dyes may cause ... -
Fijación de dendrímeros antigénicos en superficies para determinación de IgE
Vida-Pol, Yolanda; Montañez-Vega, María Isabel; Mesa, Pablo; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2016-02-15)Actualmente, el diseño de nuevos materiales con potenciales aplicaciones biomédicas es de gran importancia , sobre todo para su uso directo en diagnóstico clínico . En particular, los dispositivos que ... -
Large-Scale Dendrimer-Based Uneven Nanopatterns for the Study of Local RGD Density Effects on Cell Adhesion
Lagunas, Anna; Castaño, Albert G; Artés, Juan M; Vida-Pol, Yolanda; Collado-Martín, Daniel; Pérez-Inestrosa, Ezequiel; Gorostiza, Pau; Claros-Gil, Silvia; Andrades-Gómez, José Antonio; Samitier, Josep[et al.] (2014)Cell adhesion processes are governed by the nanoscale arrangement of the extracellular matrix (ECM), being more affected by local rather than global concentrations of cell adhesive ligands. In many cell-based studies, ... -
Managing with (fluorescent)-biomimetic dendrimers
Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Collado-Martín, Daniel; Nájera-Albendín, Francisco; Mesa-Antunez, Pablo; Ruiz-Sanchez, Antonio Jesus; Molina, Noemi; Morgado, Anjara[et al.] (2017-06-30)Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes. Diagnosis via specific interactions with target proteins is one of the objectives that has been given more ...