• Behavior of osteoprogenitor cells on EBM-sintered Ti6Al4V-scaffolds coated RGD-presenting hemidendrons. Implications for prosthesis design 

      González, Ana; Cabeza, Noemí; Vida-Pol, Yolanda; Pérez-Inestrosa, Ezequiel; Santos-Ruiz, Leonor; [et al.] (2017-12-12)
      Titanium-based prosthetic implants are commonly used in Traumatology and Maxillofacial Surgery to achieve functional recovery of a severely damaged bones. Prosthetic replacements fail in the long term due to poor ...
    • Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic 

      Vida-Pol, Yolanda; Collado, Daniel; Najera-Albendin, Francisco; Montañe, M I; Perez-Inestrosa, E; [et al.] (2013-09-25)
      The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ...
    • Design and synthesis of new dendrons for biomedical applications 

      Morgado, Anjara; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel (2020-03-30)
      Dendrons are excellent multifunctional platforms for many different applications. In particular, the development of multivalent molecular nanostructures, with a well-defined size and shape, has an enormous interest in the ...
    • Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition 

      Najera-Albendin, Francisco; Montañez, María Isabel; Ruiz-Sánchez, Antonio Jesús; Vida-Pol, Yolanda; Collado, Daniel; [et al.] (2014-06-12)
      Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ...
    • Diseño y síntesis de nuevos dendrímeros 

      Morgado, Anjara; Molina, Noemi; Collado, Daniel; Najera-Albendin, Francisco; Vida-Pol, Yolanda; [et al.] (2018-03-06)
      Los dendrímeros son excelentes plataformas multifuncionales para una gran cantidad de diferentes aplicaciones. En particular, el desarrollo de nanoestructuras moleculares multivalentes, con tamaño y forma bien definida, ...
    • Diseño y síntesis de nuevos dendrímeros y dendrones. Aplicaciones en regeneración tisular 

      Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Collado, Daniel; Najera-Albendin, Francisco; [et al.] (2018-03-06)
      Los dendrímeros han generado un enorme interés debido a su particular estructura ramificada y su multivalencia. La extensa investigación que se ha llevado a cabo sobre este tipo de macromoléculas ha demostrado la naturaleza ...
    • Diseño y síntesis de nuevos dendrones para aplicaciones biomédicas 

      Molina, Noemi; Morgado, Anjara; Collado, Daniel; Najera-Albendin, Francisco; Vida-Pol, Yolanda; [et al.] (2018-03-06)
      Los dendrímeros han sido empleados en una gran variedad de aplicaciones, entre las que destacan las del campo de la biomedicina. Estas macromoléculas multivalentes ofrecen la posibilidad de incorporar múltiples funcionalidades ...
    • Energy transfer in Aminonaphthalimide-BODIPY dyads upon one and two photons excitation 

      Collado, Daniel; Vida-Pol, Yolanda; Najera-Albendin, Francisco; Pérez-Inestrosa, Ezequiel (2014-07-03)
      BODIPY dyes are nowadays widely commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry [1]. However, the generally very small Stokes shifts of BODIPY dyes may cause ...
    • Fijación de dendrímeros antigénicos en superficies para determinación de IgE 

      Vida-Pol, Yolanda; Montañez, María Isabel; Mesa, Pablo; Collado, Daniel; Najera-Albendin, Francisco; [et al.] (2016-02-15)
      Actualmente, el diseño de nuevos materiales con potenciales aplicaciones biomédicas es de gran importancia , sobre todo para su uso directo en diagnóstico clínico . En particular, los dispositivos que ...
    • Managing with (fluorescent)-biomimetic dendrimers 

      Perez-Inestrosa, Ezequiel; Vida-Pol, Yolanda; Collado, Daniel; Najera-Albendin, Francisco; Mesa-Antunez, Pablo; [et al.] (2017-06-30)
      Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes. Diagnosis via specific interactions with target proteins is one of the objectives that has been given more ...
    • One and two-photons excitation of aminonaphthalimide–bodipy dyads: biological application 

      Vida-Pol, Yolanda (2014-07-25)
      Boron dipyrromethene (BODIPY) dyes are commonly commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry. However, the generally very small Stokes shifts of BODIPY dyes ...
    • Preparation of Dendrimeric antigen-silica particle composites 

      Gil-Ocaña, Violeta; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel (2020)
      The desing and synthesis of new materials for biomedical applications is a high-priority research topic in a great number of biomedical areas. Moreover, advances in the fabrication of these materials are of growing interest ...
    • Preparation, photophysical properties and cell image of Naphthalimide-based fluorescent nanostructures for biomedical applications: BAPAD dendrimeric antigens and silica nanoparticles 

      Mesa, Pablo; Collado, Daniel; Vida-Pol, Yolanda; Najera-Albendin, Francisco; Pérez-Inestrosa, Ezequiel (2014-07-17)
      We present here the synthesis and characterization of BAPAD [1] fluorescent Dendrimeric-Antigens (DeAn), to be applied in basophil activation as a test to detect drug allergy reactions. A second generation BAPAD dendrimer ...
    • Pt(II)-dendrimers as bio-imaging marker for bacteria in two-photon excitation microscopy 

      Vida-Pol, Yolanda; Molina, Noemi; Cnudde, Marvin; Guadix, Juan A.; Perez-Pomares, Jose Maria; [et al.] (2019-07-25)
      The use of luminescent markers based on metal complexes in two-photon excitation microscopy techniques are of great interest in the field of bioimaging. However, despite the excellent luminescent properties of Pt(II) ...
    • RGD peptide on Dendrimer surfaces Affects Mesenchymal Stem Cells Adhesion 

      Vida-Pol, Yolanda; Molina, Noemi; Collado, Daniel; Najera-Albendin, Francisco; Lagunas, Anna; [et al.] (2016-04-07)
      Mesenchymal stem cells (MSCs) are promising candidates for a range of tissue regeneration applications. Adequate scaffolds are necessary for their application in vivo, where interactions between cells and the surface ...
    • RGD-dendritic structures on titanium alloy. Influence in the relationship between bone cells and the metal surface 

      Molina, Noemí; Gonzalez-Luque, Ana M.; Becerra-Ratia, Jose; Santos-Ruiz, Leonor; Vida-Pol, Yolanda; [et al.] (2019-09-18)
      Prosthetic implants are used in surgical procedures to replace a joint (hip or knee) allowing the functional recovery of the patient. Prostheses are usually made of titanium alloys. However, the lack of chemical and ...
    • Sistema fluorescentes multifotónicos con aplicaciones en bioimagen 

      Collado, Daniel; Perez-Inestrosa, Ezequiel; Vida-Pol, Yolanda; Najera-Albendin, Francisco; Ramon, Patricia; [et al.] (2013-09-20)
      Los colorantes y las sondas fluorescentes son componentes clave en el estudio de muestras biológicas mediante microscopía de fluorescencia. Mientras que muchos colorantes fluorescentes disponibles comercialmente han sido ...
    • Syntehsis and use of dendrimeric structures as a tool in biomedicine 

      Perez-Inestrosa, Ezequiel; Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Najera-Albendin, Francisco (2019-10-28)
      Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density ...
    • Synthesis and Biomedical aplications of BAPAD: Bisaminoalkylpolyamide Dendrimers 

      Perez-Inestrosa, Ezequiel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado, Daniel; Najera-Albendin, Francisco; [et al.] (2014-02-06)
      A new class of Dendrimeric Systems (Dendrimers and Dendrons) and the study of their properties in molecular recognition processes are presented. These Dendrimers (BAPAD: BisAminoalkylPolyAmideDendrimers), are designed to ...
    • Synthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cells 

      Mesa-Antunez, Pablo; Collado, Daniel; Vida-Pol, Yolanda; Najera-Albendin, Francisco; Fernandez, Tahia; [et al.] (Servicio de Publicaciones de la Universidad de Huelva, 2016)
      A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide ...