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Listar por autor "Arrabal-García, Pilar María"
Mostrando ítems 1-7 de 7
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A collagen-targeted biomimetic RGD peptide to promote osteogenesis
Visser, Rick; Arrabal-García, Pilar María; Santos-Ruiz, Leonor; Fernández-Barranco, Raúl; Becerra-Ratia, José; Cifuentes-Rueda, Manuel[et al.] (MARY ANN LIEBERT, INC, 2014-01)Osteogenesis is a complex, multifactorial process in which many different signals interact. The bone morphogenetic proteins (BMPs) are the most potent inducers of osteoblastic differentiation, although very high doses of ... -
A model of maxilla resection to test new hybrid implants:macroporous titanium and tissue engineering elements
Santos-Ruiz, Leonor; Monopoli, Donato; Yáñez Vilas, José Ignacio; Mentado, Belinda; Ruiz, F; Argárate, N; Granados, F; Arrabal-García, Pilar María; Belmonte, Rosa María; Becerra-Ratia, José[et al.] (2015-07-23)Maxillary bone loss in commonly found in humans, due to bone ageing, tooth loos, periodontal disease and, more severely, to trauma, radiotherapy and tumor resection. Masillofacial reconstructive surgery is a still unmet ... -
A synthetic collagen-binding arg-gly-asp (rgd) biomimetic peptide enhances bone cell differentiation
Visser, Rick; Arrabal-García, Pilar María; Santos-Ruiz, Leonor; Fernández-Barranco, Raúl; Cifuentes-Rueda, Manuel; Becerra-Ratia, José[et al.] (2013-11-27)RGD (arginine-glycine-aspartic acid) peptides have shown some promising abilities to promote the attachment of cells to biomaterials and to direct their differentiation. However, anchoring these peptides to the biomaterial’s ... -
Basic fibroblast growth factor enhances the osteogenic differentiation induced by bone morphogenetic protein-6 in vitro and in vivo
Visser, Rick; Arrabal-García, Pilar María; Santos-Ruiz, Leonor; Becerra-Ratia, José; Cifuentes-Rueda, Manuel (ELSEVIER, 2012-04)Some members of the bone morphogenetic protein subfamily (BMP-2 and -7) are currently used in orthopedic surgery for several applications. Although their use is considered safe at short term, the high doses of growth factors ... -
Bone marrow mesenchymal stem cells, collagen scaffold and BMP-2 for rat spinal fusio
Arrabal-García, Pilar María; Visser, Rick; Cifuentes-Rueda, Manuel; Becerra-Ratia, José; Jiménez-Enjuto, E. (2013-11-08)The use of autograft for posterolateral spinal fusion, continue being considered the gold standard for the treatment of spine pathologies. However, due to complications such as donor site morbidity, increased operating ... -
Osteogenic molecules for clinical applications: Improving the BMP-collagen system
Arrabal-García, Pilar María; Visser, Rick; Santos-Ruiz, Leonor; Becerra-Ratia, José; Cifuentes-Rueda, Manuel (Sociedad de Biología de Chile, 2013)Among the osteogenic growth factors used for bone tissue engineering, bone morphogenetic proteins (BMPs) are the most extensively studied for use in orthopaedic surgery. BMP-2 and BMP-7 have been widely investigated for ... -
The effect of combining bone morphogenetic proteins -2 and -6 on osteoblastic differentiation and bone
Rico-Llanos, Gustavo Adolfo; Bodnárová, Kristina; Arrabal-García, Pilar María; Cifuentes-Rueda, Manuel; Becerra-Ratia, José (2015-07-21)Bone morphogenetic proteins-2 and -7 (BMP-2 and -7) are the only two members of the BMP subfamily approved to date to be used in combination with collagen type I in orthopedic surgery, although other BMPs have proven to ...