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Listar por autor "Blanco-Calvo, Eduardo"
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A dynamic expression pattern of sGalpha(i2) protein during early period of postnatal rat brain development.
López-Aranda, Manuel Francisco; López-Téllez, Juan Félix; Blanco-Calvo, Eduardo; Masmudi-Martín, Mariam; Navarro-Lobato, Irene; Khan, Zafaruddin
[et al.] (Elsevier, 2008-10-07)
The function of sG alpha i2 protein in central nervous system is not well understood. Therefore to explore the possible role of this protein in postnatal brain development, we have analyzed the protein expression pattern ... -
Activation of caspase-3 pathway by expression of sGαi2 protein in BHK cells.
López-Aranda, Manuel Francisco; Navarro-Lobato, Irene; López-Téllez, Juan Félix; Blanco-Calvo, Eduardo; Masmudi-Martín, Mariam; Khan, Zafaruddin
[et al.] (Elsevier, 2008)
Treatment with dopamine and other dopamine D2 receptor agonists has been shown to induce cell death through activation of caspase-3 pathway. However, initial step that leads to the activation of caspase-3 in D2 receptor-mediated ... -
Attenuation of cocaine-induced conditioned locomotion is associated with altered expression of hippocampal glutamate receptors in mice lacking LPA1 receptors.
Blanco-Calvo, Eduardo; Bilbao, Ainhoa; Luque-Rojas, María Jesús
; Palomino, Ana; Bermúdez Silva, Francisco Javier; Suárez-Pérez, Juan
; Santín-Núñez, Luis Javier
; Estivill-Torrús, Guillermo; Gutiérrez-Pérez, Antonia
; Campos-Sandoval, José A.; Márquez-Gómez, Javier
; Rodriguez-de-Fonseca, Fernando[et al.] (Springer, 2012)
Lysophosphatidic acid is a phospholipid mediator that modulates neurodevelopment and neurogenesis in the hippocampus through its actions on LPA1 receptors. Emerging evidences support LPA1 as a mediator of learning and ... -
Cocaine modulates both glutaminase gene expression and glutaminase activity in the brain of cocaine-sensitized mice
Blanco-Calvo, Eduardo; Campos-Sandoval, José Ángel
; Palomino, Ana; Luque-Rojas, María Jesús
; Bilbao, Ainhoa; Suárez, Juan; Márquez-Gómez, Javier
; Rodriguez-de-Fonseca, Fernando[et al.] (Springer, 2012)
Glutaminase is considered the main Glutamate (Glu) producing enzyme. Two isoforms, liver (LGA) and kidney (KGA) type glutaminases have been identified in neurons. The role of both enzymes in psychopharmacological responses ... -
Efectos de la Palmitoiletanolamida en la adicción a cocaína: influencia en la sensibilización conductual y en el condicionamiento preferencial de lugar.
Zambrana-Infantes, Emma (UMA Editorial, 2016)La adicción a cocaína supone un problema, tanto a nivel individual como social, puesto que conlleva numerosas complicaciones sanitarias para los consumidores e importantes costes económicos para el sistema de salud. La ... -
Effects of palmitoylethanolamide in cocaine-induced behaviours
Santín-Núñez, Luis Javier; Zambrana-Infantes, Emma; Galeano, Pablo; Rosell-del-Valle, Cristina; Ladrón de Guevara-Miranda, David; Castilla-Ortega, María Estela
; Rodriguez-de-Fonseca, Fernando; Blanco-Calvo, Eduardo
[et al.] (2016-07-13)
Aims. Cocaine addiction is a chronically relapsing disorder characterized by the compulsion to seek and take the drug. Previous investigations have demonstrated that several drugs of abuse, as cocaine, can alter the levels ... -
Glutaminase and MMP-9 Downregulation in Cortex and Hippocampus of LPA1 Receptor Null Mice Correlate with Altered Dendritic Spine Plasticity
Peñalver Alonso, Ana; Campos-Sandoval, José Ángel; Blanco-Calvo, Eduardo
; Cardona Ramírez, Carolina; Castilla, Laura; Martín-Rufián, Mercedes; Estivill-Torrús, Guillermo; Sánchez-Varo, Raquel María
; Alonso-Carrión, Francisco José
; Pérez-Hernández, Mercedes; Colado, María Isabel; Gutiérrez-Pérez, Antonia
; Rodriguez-de-Fonseca, Fernando; Márquez-Gómez, Javier
[et al.] (Frontiers, 2017-09-05)
Lysophosphatidic acid (LPA) is an extracellular lipid mediator that regulates nervous system development and functions acting through G protein-coupled receptors (GPCRs). Here we explore the crosstalk between LPA1 receptor ... -
Reduction of adult hippocampal neurogenesis modifies brain functional connectivity and enhances cocaine-seeking in mice
Castilla-Ortega, María Estela; Ladrón de Guevara-Miranda, David; Blanco-Calvo, Eduardo
; Serrano, Antonia; Pedraz, María; Estivill-Torrús, Guillermo; Pavón-Morón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier
[et al.] (2015-09-16)
Recently, adult hippocampal neurogenesis has been proposed as a putative neuroplastic mechanism involved in those behavioural processes. In this work, we studied the effect of the inhibition of adult hippocampal neurogenesis ...