Listar por autor "Burgos-Molina, Antonio Manuel"
Mostrando ítems 1-20 de 46
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Acquisition resistance to bleomycin deregulates HSP77 and HSP60 proteins in response to stress
Burgos-Molina, Antonio Manuel
; Alamilla Presuel, Juan Carlos; Mercado-Sáenz, Silvia; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
The HSP77 and HSP60 protein overexpression is implicated in bleomycin resistance. The resistant adquisition to antineoplastic drugs deregulate proteins involved in response to stress factors. -
Analysis of Immunotherapy in hepatocellular carcinoma
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
One reason immunotherapy is important for Hepatocellular carcinoma, it’s because there are many immune cells in that organ. Because HCC is very aggressive, immunotherapy must be applied correctly. There are a lot of ... -
Analysis of Immunotherapy in Lung cancer
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
There are many ways of immunotherapy for lung cancer, and that includes the use of drugs, molecular treatment, and even the combination with radiotherapy. But also, it’s important to investigate in the future the adverse ... -
Analysis of Immunotherapy in ovarian cancer
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
There are many Immunotherapy methods in ovarian cancer. Even the immune cells themselves can be part of the immunotherapy. But also at molecular level, the immunotherapy can be applied, like maintaining damage in DNA or ... -
Analysis of Immunotherapy in Triple negative breast cancer
Burgos-Molina, Antonio Manuel; Alamilla Presuel, Juan Carlos; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
TNBC cancer is complicated, most is about PD-L1 mechanism. Too many kinds of immunotherapy have been developed to treat TNCB. Nowadays, is complicated a fast and 100% accurate treatment for TNBC, because of cancer complications ... -
AURKA, BIRC5 and PLK1 as potential biomarkers of response in radiation-resistant colorectal cancer
Burgos-Molina, Antonio Manuel; Rodríguez-García, M.; González-Vidal, A.; Mercado-Sáenz, Silvia; Ruiz-Gómez, Miguel José (ASEICA, 2024-11)
The study demonstrated that AURKA, BIRC5 and PLK1 proteins are hyper-expressed in patients affected by colon and rectum adenocarcinoma resistant to radiotherapy. The validation of the expression levels in patient samples ... -
Beneficial interactions between the microbiota and the host increase immunity for a better response to treatment of cancer patients
Burgos-Molina, Antonio Manuel; González Vidal, Alejandro; Mercado-Sáenz, Silvia; Alamilla Presuel, Juan Carlos; Ruiz-Gómez, Miguel José (2022)
Numerous beneficial interactions between microbiota and host contribute to produce nutrients, metabolites, immunoglobulins and an increase in lymphocytes. The correct colonization of the intestine by microbiota induces a ... -
Cancer immunotherapy as a new treatment option
Burgos-Molina, Antonio Manuel; Padín-López, Alba; Alonso-Ortiz, Antonio (2019-01-16)
Cancer can coaptate the immune control of the immune system (IS), evade immunity and its destruction. So, could we say openly that immunotherapy is a viable treatment option for patients with advanced cancer? Yes, ... -
Case study of the intestinal microbiota using the XGN-MBI metagenomic assay
Burgos-Molina, Antonio Manuel; Mercado-Sáenz, Silvia; Gil-Carmona, Luisa; Morales-Moreno, Francisco; Ruiz-Gómez, Miguel José (2019-01-17)
The microbiota of the colon and rectum is the most abundant and diverse of the human body, with a density of up to 1-2 kg of weight and a diversity that exceeds a thousand species. Metagenomics can be defined as the ... -
Cellular microenvironment can be modulated by factors influenced by microbiota to improve cancer treatment
Burgos-Molina, Antonio Manuel; González Vidal, Alejandro; Mercado-Sáenz, Silvia; Alamilla Presuel, Juan Carlos; Ruiz-Gómez, Miguel José (2022)
Numerous environmental factors affect the ecosystem of the microbiota, so its composition and diversity can be modified by changes produced in these factors. These alterations can facilitate the appearance of pathological ... -
Clinical metagenomic analysis and Cancer
Burgos-Molina, Antonio Manuel; Mercado-Sáenz, Silvia; Morales Moreno, Francisco; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (Aseica, 2022)
After seven years of periodic controls by the SEIMC (Spanish Society of Infectious Diseases and Clinical Microbiology), it can be affirmed that the analysis is capable of detecting microorganisms in any type of sample ... -
Construction techniques and architectural design to reduce the level of radon inside buildings and therefore the risk of cancer
Burgos-Molina, Antonio Manuel; Ruiz-González, Óscar M.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
The incorporation of anti-radon membranes and forced ventilation and depressurization systems in buildings contributes to reduce the concentration of radon inside rooms. In this way, the exposure to radiation in its ... -
Electromagnetic pollution in the urban environment and risk or cancer
Burgos-Molina, Antonio Manuel; Ruiz-González, O.M.; Ledesma-Tomé, F.A.; Soto-Pinilla, J.; Sánchez-Jiménez, M.; González-Vidal, A.; Ruiz-Gómez, Miguel José[et al.] (ASEICA, 2024-11)
Social, national and international interest in the health risks of exposure to electromagnetic fields in the urban environment is growing in our increasingly technological Society. In Spain, very few measurements have been ... -
Exposure of cancer cells to heat shock protein inhibitors induces decreased tumour survival
Burgos-Molina, Antonio Manuel; Peinado-Ruiz, Isabel C.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
All tumour studied show an increase in resistance to treatment and an increase in cell survival. This response is related to an increase in the heat shock protein HSP90, since it participates in the assembly of telomerase, ... -
Health risk from chemical contaminants in building construction.
Burgos-Molina, Antonio Manuel; Sánchez-Jiménez, M.; Ruiz-González, Óscar M.; Ledesma-Tomé, F.A.; Soto-Pinilla, J.; González-Vidal, Alejandro; Ruiz-Gómez, Miguel José[et al.] (ASEICA, 2024)
Currently, multiple materials that include toxic contaminants continue to be used in the construction of buildings, which can cause multiple diseases, especially affecting the respiratory system, and the appearance of ... -
Heat shock proteins overexpressed in tumour cells and their relationship with ageing and cellular resistance to treatment
Burgos-Molina, Antonio Manuel; Peinado-Ruiz, Isabel C.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
The increase in the concentration of HSP in tumour cells produces an increase in the capacity for replication, migration, and drug resistance. HSP and HSF1 factor are involved in the etiology of breast cancer. The ... -
Identificación de nuevas proteínas relacionadas con la resistencia a radiación ionizante y el envejecimiento celular en S. cerevisiae
(UMA Editorial, 2023-03-03)Introducción: La aparición de resistencia a radiación en células tumorales expuestas constituye un problema en el abordaje terapéutico de algunos tumores. La radiorresistencia es una preocupación grave, pues provoca un ... -
In silico analysis to identify the core genes implicated in colorectal cancer radiation resistance.
Burgos-Molina, Antonio Manuel; Rodríguez-García, Marta; González-Vidal, Alejandro; Mercado-Sáenz, Silvia; Ruiz-Gómez, Miguel José (2024)
Twenty-one proteins have been identified that act with different molecular mechanisms and that, to a greater or lesser extent, induce radiation resistance in colorectal cancer cells that overexpress them. The in-silico ... -
Increased resistance to drugs and longer life cycle by the administration of exogenous agents to normal human cells
Burgos-Molina, Antonio Manuel; Peinado-Ruiz, Isabel C.; González Vidal, Alejandro; Ruiz-Gómez, Miguel José (2022)
Exogenous HSP70 provides protection against oxidative stress and that it could be a good therapeutic strategy to treat age-related macular degeneration. On the other hand, externally inoculating a heat shock protein to ... -
Intestinal microbiota and colorectal cancer
Burgos-Molina, Antonio Manuel; Mercado-Sáenz, Silvia; Morales-Moreno, Francisco; Gil-Carmona, Luisa; Ruiz-Gómez, Miguel José (2019-01-16)
Colorectal cancer may be influenced by changes in the intestinal microbiota that affect the mucosa and cause an immune response capable of producing inflammatory effects. Although there are still few studies in this regard, ...