Listar por autor "Cardona-Díaz, Fernando"
Mostrando ítems 1-16 de 16
-
Association between metabolic status and the methylation level of genes involved in metabolic disorders and obesity
Castellano-Castillo, Daniel; Moreno-Indias, Isabel; Picon-Cesar, María José; Garcia-Aleman, Jorge; Macias-Gonzalez, Manuel; Tinahones-Madueño, Francisco José
; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (2014-08-01)
Objectives: DNA methylation is one of the epigenetic mechanims to control gene expression, and it is believed to be modulated by environmental and nutritional factors. Thus, epigenetics provides a mechanism which may explain ... -
Effect of acute and chronic red wine consumption on lipopolysaccharide concentrations
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Boto-Ordóñez, María; Coín-Aragüez, Leticia I.; Roca-Rodríguez, María del Mar; Delgado-Lista, J.; Cardona-Díaz, Fernando; Andrés-Lacueva, Cristina; Tinahones-Madueño, Francisco José[et al.] (Elsevier (The American Journal of Clinical Nutrition), 2013)
Background: Chronic red wine (RW) consumption has been associated with decreased cardiovascular disease risk, mainly attributed to an improvement in lipid profile. RW intake is also able to change the composition of gut ... -
Effect of apolipoprotein C3 and apolipoprotein A1 polymorphisms on postprandial response to a fat overload in metabolic syndrome patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Valdivieso-Felices, Pedro; Tinahones-Madueño, Francisco José; Cardona-Díaz, Fernando (Elsevier. The Canadian Society of Clinical Chemists., 2010)
Objectives: Apolipoprotein C-III (APOC3) is a component of triglyceride rich lipoproteins, and SstI polymorphism has been associated with hypertriglyceridemia. Apolipoprotein A-I (APOA1) is the major component of HDL and ... -
Endotoxin increase after fat overload is related to postprandial hypertriglyceridemia in morbidly obese patients
Clemente-Postigo, María Mercedes; Queipo-Ortuño, María Isabel; Murri, Mora; Boto-Ordóñez, María; Pérez-Martínez, Pablo; Andrés-Lacueva, Cristina; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (American Society for Biochemistry and Molecular Biology, 2012)
The low-grade inflammation observed in obesity has been associated with a high-fat diet, though this relation is not fully understood. Bacterial endotoxin, produced by gut microbiota, may be the linking factor. However, ... -
FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels
Queipo-Ortuño, María Isabel; Escoté Miró, Xavier; Ceperuelo-Mallafré, Victoria; Garrido-Sánchez, Lourdes; Miranda, Merce; Clemente-Postigo, María Mercedes; Pérez-Pérez, Rafael; Peral Fuentes, Belén; Cardona-Díaz, Fernando; Fernández Real, José M; Tinahones-Madueño, Francisco José; Vendrell Ortega, Joan[et al.] (PLOS (Public Library of Science), 2012)
Background FABP4 is predominantly expressed in adipose tissue, and its circulating levels are linked with obesity and a poor atherogenic profile. Objective In patients with a wide BMI range, we analyze FABP4 expression ... -
Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers
Queipo-Ortuño, María Isabel; Boto-Ordóñez, María; Murri Pierri, Mora; Gómez-Zumaquero, Juan Miguel; Clemente-Postigo, María Mercedes; Estruch, Ramón; Cardona-Díaz, Fernando; Andrés-Lacueva, Cristina; Tinahones-Madueño, Francisco José[et al.] (Elsevier (American Society for Nutrition), 2012)
Background: Few studies have investigated the effect of dietary polyphenols on the complex human gut microbiota, and they focused mainly on single polyphenol molecules and select bacterial populations. Objective: The ... -
Lipopolysaccharide and lipopolysaccharide-binding protein levels and their relationship to early metabolic improvement after bariatric surgery
Clemente-Postigo, María Mercedes; Roca-Rodríguez, María del Mar; Camargo, Antonio; Ocaña-Wilhelmi, Luis Tomás; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (Elsevier (American Society for Metabolic and Bariatric Surgery), 2015)
Background: Bariatric surgery usually results in metabolic improvements within a few days from intervention, but the underlying mechanism is not completely understood and may vary depending on the bariatric procedure. ... -
Metabolic endotoxemia in obesity. Influence of dietary intervention and bariatric surgery.
(UMA Editorial, 2017-07-25)Antecedentes. Aunque la obesidad aparece frecuentemente asociada al desarrollo de enfermedades metabólicas, también existen sujetos obesos sin alteraciones metabólicas. La inflamación de bajo grado se ha propuesto como uno ... -
Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity
Clemente-Postigo, María Mercedes; Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Ramos-Molina, Bruno; Giráldez-Pérez, Rosa María; Lhamyani, Said; Alcaide Torres, Juan; Pérez-Martínez, Pablo; El Bekay Rizky, Rajaa; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (American Physiological Society, 2019)
Impaired adipose tissue (AT) lipid handling and inflammation is associated with obesity-related metabolic diseases. Circulating lipopolysaccharides (LPSs) from gut microbiota (metabolic endotoxemia), proposed as a triggering ... -
New insights in the regulation of IGFPBs by PPARG2 to protect against insulin resistance in morbid obesity.
Moreno Santos, Inmaculada; Castellano-Castillo, Daniel; Cardona-Díaz, Fernando; Garrido, Lourdes; García-Fuentes, Eduardo; Tinahones-Madueño, Francisco José; Macías-González, Manuel[et al.] (2012-06-28)
his study examines the role of PPARγ2 and IGFBPs in visceral adipose tissue of morbidly obese patients with varying insulin resistance (IR). PPARγ2 expression was lower in those with high IR, while IGFBP-2 showed protective ... -
Postprandial hypertriglyceridemia predicts improvement in insulin resistance in obese patients after bariatric surgery.
Tinahones-Madueño, Francisco José; Queipo Ortuño, Maria Isabel; Clemente-Postigo, María Mercedes; Fernandez-García, Diego; Mingrone, Geltrude; Cardona-Díaz, Fernando[et al.] (Elsevier, 2013)
Morbidly obese patients have associated diseases, such as diabetes, hypertension, hyperlipidemia, and cardiovascular disease. Bariatric surgery improves these obesity-related co-morbidities, including insulin resistance. ... -
Relación de la obesidad y la diabetes tipo 2 con los niveles plasmáticos de vitamina D y con la expresión génica del receptor de vitamina D en tejido adiposo.
Muñoz-Garach, Araceli; Clemente-Postigo, María Mercedes; Garrido López, Lourdes; Bernal-López, Rosa; Moreno-Santos, Inmaculada; Castellano-Castillo, Daniel; Fernández-García, Diego; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José; Macías-González, Manuel[et al.] (Elsevier, 2013-05-15)
Introducción: Se ha descrito que la deficiencia de vitamina D está asociada con la obesidad y la diabetes. Sin embargo, los re- sultados de los diferentes estudios no llegan a ser del todo conclu- yentes. Asimismo, se ha ... -
Relación de los niveles de vitamina D y la expresión de VDR en tejido adiposo con el índice de masa corporal y el perfil glucémico.
Clemente-Postigo, María Mercedes; Muñoz-Garach, Araceli; Garrido-Sánchez, Lourdes; Bernal-López, Rosa; Moreno-Santos, Inmaculada; Castellano-Castillo, Daniel; Fernández-García, Diego; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José; Macías-González, Manuel[et al.] (2012)
Este estudio analizó la relación entre los niveles de vitamina D (25(OH)D3), la expresión del receptor de vitamina D (VDR) en tejido adiposo visceral, el índice de masa corporal (IMC) y el perfil glucémico en 119 sujetos ... -
RNA expression changes driven by altered epigenetics status related to NASH etiology
Castellano Castillo, Daniel; Ramos-Molina, Bruno; Frutos, María Dolores; Arranz-Salas, Isabel María; Reyes-Engel, Armando; Queipo-Ortuño, María Isabel; Cardona-Díaz, Fernando[et al.] (ELSEVIER, 2024-04)
Non-alcoholic fatty liver disease (NAFLD) is a growing health problem due to the increased obesity rates, among other factors. In its more severe stage (NASH), inflammation, hepatocellular ballooning and fibrosis are ... -
Role of intestinal microbiota composition in colorectal cancer and in the response to neoadjuvant radiochemotherapy previous to surgery
(UMA Editorial, 2022-01-25)Intestinal-microbiota has been associated with different diseases, among which are obesity and colorectal cancer (CRC), microbiota is assumed to be a possible link between both disorders. Due to this, the composition of ... -
Serum 25-Hydroxyvitamin D and Adipose Tissue Vitamin D Receptor Gene Expression: Relationship with Obesity and Type 2 Diabetes
Clemente-Postigo, María Mercedes; Muñoz Garach, Araceli; Serrano, Marta; Garrido-Sánchez, Lourdes; Bernal-López, María Rosa; Fernandez-García, Diego; Moreno Santos, Inmaculada; Garriga, Nuria; Castellano-Castillo, Daniel; Camargo, Antonio; Fernández Real, José M; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José; Macías-González, Manuel[et al.] (Endocrine Society, 2015)
Context: The relationship between 25-hydroxyvitamin D [25(OH)D] and obesity and type 2 diabetes is not completely understood. Vitamin D receptor (VDR) expression in adipose tissue (AT) is related to obesity and might be ...