Listar por autor "Durán-Jimenez, Iván Jesús"
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Bone organoid generation based on double scaffolding.
Decellularized bone matrix ( is a classic approach in bone tissue engineering based on the removal of bone tissue cells and the calcified phase using chemical, physical o enzymatic agents The resulting matrix preserves ... -
DEPTOR promotes bone marrow adipose tissue expansion in calorie restricted mice.
Elevated levels of fat in bones is a characteristic feature of osteoporosis and other skeletal disorders. While the molecular mechanism behind this shift between bone and fat formation remains incompletely understood, it ... -
Mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia
Barad, M.; Csukasi, Fabiana; Krakow, D.; Durán-Jimenez, Iván Jesús
(2020-09-24)
In addition to its structural role in skeletogenesis, the extracellular matrix (ECM), particularly basement membrane proteins, facilitates communication with intracellular signaling pathways and cell to cell interactions ... -
The Skeletal Atlas: A holistic approach to transcriptomics in the skeleton.
Pérez-Tejeiro, José Miguel; Csukasi, Fabiana; Becerra-Ratia, José; Durán-Jimenez, Iván Jesús; Fernández-Pozo, Noé (2023)
Gene expression atlases are powerful bioinformatics tools that allow access to the scientific community to explore omics data. In biomedicine, numerous gene expression databases are available, yet none provide enough ...