Listar por autor "Gago-Calderon, Belen"
Mostrando ítems 1-20 de 37
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A model of increased impulsivity in rats with bilateral parkinsonism treated with Pramipexole
Gago-Calderon, Belen
; Jimenez-Urbieta, Haritz; Marin, Concepció; Quiroga-Varela, Ana; Delgado-Alvarado, Manuel; Rodriguez-Oroz, María Cruz[et al.] (2016)
Impulse control disorders (ICD) is a common side effect of the dopaminergic treatment in patients with Parkinson's disease, which is more associated with dopamine agonists than with levodopa. To understand its pathophysiology, ... -
Antidepressant-like effects induced by galanin 2/neuropeptide Y Y1 heterodimers in the dentate gyrus of the hippocampus
Narváez, Manuel; Borroto-Escuela, Dasiel; Millon-Peñuela, Carmelo; Gago-Calderon, Belen; Flores-Burgess, Antonio; Santin-Nuñez, Luis Javier; Fuxe, Kjell; Narváez, José Ángel; Díaz-Cabiale, Zaida[et al.] (2017-08-30)
Previously, we have described the Galanin (GAL) and Neuropeptide Y Y1 (NPYY1) interactions through GAL receptor 2 and NPYY1 receptor 1 (GALR2/NPYY1R) heterodimers in the Dentate Gyrus (DG) of the Hippocampus, using ... -
Different susceptibility to pramipexole-induced impulsivity in a rat model of parkinson’s disease
Jimenez-Urbieta, Haritz; Merino-Galan, Leire; Rodriguez-Chinchilla, Tatiana; Belloso-Iguerategui, Arantzatzu; Delgado-Alvarado, Manuel; Navalpotro-Gómez, Irene; Quiroga-Varela, Ana; Gago-Calderon, Belen; Rodríguez-Oroz, María Cruz[et al.] (2019-09-12)
Impulse Control Disorders (ICD) in patients with Parkinson’s disease are abnormal behaviors caused by long-term use of dopamine agonists, which pathophysiology is poorly understood. Using parkinsonian rats (adeno-associated ... -
Dopamine D4 receptor activation counteracts nigrostriatal pathway activation by morphine: relevance in drug addiction.
Rivera-Ramirez, Alicia; Suárez-Boomgaard, Diana; Gago-Calderon, Belen; Valderrama-Carvajal, Alejandra; Medina-Luque, José; Roales-Buján, Ruth; Fuxe, Kjell; De-la-Calle-Martin, Adelaida[et al.] (2013)
Morphine induces dopamine release in the caudate putamen (CPu), which promotes stereotyped behavior and habit learning for drug-seeking and –taking. Nigrostriatal pathway stimulation by morphine is due to a removal of tonic ... -
Dopamine D4R restores morphine-induced impairment of adult neurogenesis in the subventricular zone
Gago-Calderon, Belen; Real-Aviles, Maria Angeles; Ponce-Velasco, Marina; Rivera-Ramirez, Alicia (2021)
In the adult mammalian brain, neuroblasts from the subventricular zone (SVZ) migrate along the rostral migratory stream into the olfactory bulb, where they differentiate and synaptically integrate to contribute with the ... -
The dopaminergic mesolimbic system are involved in the anhedonic-like effects produced by galanin (1-15) in rats.
Cantero-García, Noelia; Garcia-Duran, Laura; Gago-Calderon, Belen; Flores-Burgess, Antonio; Alén, Francisco; Orio, Laura; Narváez, José Ángel; Fuxe, Kjell; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo; Garcia-Duran, Laura[et al.] (2019-09-10)
Galanin (1-15)[GAL(1-15)] induces depressant- and anxiogenic-like actions in several behavioural tests. Recently, we described that GAL(1-15) induces an anhedonic-like effect in saccharine self-administration and sucrose ... -
The effect of Galanin N-Terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system.
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderon, Belen; Garcia-Duran, Laura; Cantero-García, Noelia; Alén, Francisco; Orio, Laura; Narváez, José Ángel; Fuxe, Kjell; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2019-11-18)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic-like actions in behavioral tests and these effects were significantly stronger than the ones induced by Galanin. Since anhedonia is a ... -
Effects of galanin n-terminal fragment (1-15) in sac- charin self-administration and sucrose preference test in rats.
Garcia-Duran, Laura; Cantero-García, Noelia; Flores-Burgess, Antonio; Gago-Calderon, Belen; Allén, Francisco; Orio, Laura; Narváez, José Ángel; Fuxe, Kjell; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo[et al.] (2019-09-12)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions in several behavioral tests, and these effects were significantly stronger than the ones induced by Galanin (1-29). Since, ... -
Effects of Galanin N-Terminal fragment (1-15) in the anhedonic behavioural tests in rats.
Garcia-Cantero, Noelia; Flores-Burgess, Antonio; Gago-Calderon, Belen; Garcia-Duran, Laura; Alén, Francisco; Orio, Laura; Narváez, José Ángel; Fuxe, Kjell; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida; Millon-Peñuela, Carmelo[et al.] (2021-01-22)
The Galanin N-terminal fragment (1-15)[GAL(1-15)] induces depressant- and anxiogenic-like actions in behavioural tests in rats. Since anhedonia is a core feature of depression, we have analyzed GAL(1-15) actions in ... -
Encapsulación de neuropéptidos mediante la técnica de co-flujo
(2018-03-22)Muchas enfermedades del sistema nervioso central (SNC) pueden ser tratadas dirigiendo fármacos a esta zona del cuerpo. Sin embargo, el camino hacia el encéfalo se ve obstaculizado por una serie de factores, constituyendo ... -
Encapsulación de neuropéptidos mediante la técnica de Electrospraying & Electrospinning coaxial
(2018-03-22)La barrera hematoencefálica (BHE) es una estructura con permeabilidad selectiva que no permite el paso de multitud de sustancias al sistema nervioso central (SNC). Algunos neuropéptidos, como la galanina, y fármacos que ... -
Galanin (1-15) enhancement of the behavioral effects of a 5-HT1AR agonist and fluoxetine in the forced swimming test gives a new therapeutic strategy against depression: possible role of GALR1-GALR2-5-HT1AR heteroreceptor complexes
Flores-Burgess, Antonio; Millon-Peñuela, Carmelo; Puigcerver-Martinez, Araceli; Gago-Calderon, Belen; Garcia-Duran, Laura; Cantero-García, Noelia; Narváez, José Ángel; Santin-Nuñez, Luis Javier; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2019-06-17)
Major Depression is the most frequent mood disorder, with a lifetime prevalence that has been reported to range from 7% to 21%. It is associated with a substantial functional impairment, diminished quality of life, increased ... -
Galanin (1-15) enhances the behavioral effects of fluoxetine in the forced swimming test: a new therapeutic strategy against depression
Flores-Burgess, Antonio; Millon-Peñuela, Carmelo; Gago-Calderon, Belen; Narváez, Manuel; Borroto-Escuela, Dasiel O.; Narváez, José Ángel; Fuxe, Kjell; Santin-Nuñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2017)
The selective serotonergic (5- HT) reuptake inhibitors, including Fluoxetine (FLX), are the most commonly used for treatment of major depression. However, the understanding of the mechanism of action of FLX beyond its ... -
Galanin (1-15) enhances the behavioural effects of escitalopram in the forced swimming test in rats
Garcia-Duran, Laura; Cantero-García, Noelia; Flores-Burgess, Antonio; Gago-Calderon, Belen; Puigcerver-Martinez, Araceli; Narváez, José Ángel; Santin-Nuñez, Luis Javier; Millon-Peñuela, Carmelo; Díaz-Cabiale, Zaida[et al.] (2021-01-22)
The selective serotonergic reuptake inhibitors (SSRIs) are the most commonly used for the treatment of major depression. Recently, we observed that the Galanin N-terminal fragment (1-15) [GAL(1-15)] enhances the ... -
Galanin decreases NPYY1R internalization and β- Arrestin2 recruitment
Narváez, Manuel; Borroto-Escuela, Dasiel; Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderon, Belen; Santin-Nuñez, Luis Javier; Fuxe, Kjell; Narváez, José Ángel; Díaz-Cabiale, Zaida[et al.] (2015-10-05)
We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers. The aim of this work was to study ... -
Galanin interacts with Neuropeptide Y Y1 receptor in the dentate gyrus of the hippocampus through GALR2/NPYY1R heterodimers
Narváez, Manuel; Borroto-Escuela, Dasiel; Millon-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderon, Belen; Santin-Nuñez, Luis Javier; Fuxe, Kjell; Narváez, José Ángel; Díaz-Cabiale, Zaida[et al.] (2016-07-11)
We have shown Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to analyze GAL/NPYY1R interactions ...