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Listar por autor "Garcia-Duran, Laura"
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The dopaminergic mesolimbic system are involved in the anhedonic-like effects produced by galanin (1-15) in rats.
Cantero-García, Noelia; Garcia-Duran, Laura; Gago-Calderon, Belen
; Flores-Burgess, Antonio
; Alén, Francisco; Orio, Laura; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
; Millon-Peñuela, Carmelo
; Garcia-Duran, Laura
[et al.] (2019-09-10)
Galanin (1-15)[GAL(1-15)] induces depressant- and anxiogenic-like actions in several behavioural tests. Recently, we described that GAL(1-15) induces an anhedonic-like effect in saccharine self-administration and sucrose ... -
The effect of Galanin N-Terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system.
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio
; Gago-Calderon, Belen
; Garcia-Duran, Laura
; Cantero-García, Noelia; Alén, Francisco; Orio, Laura; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
[et al.] (2019-11-18)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic-like actions in behavioral tests and these effects were significantly stronger than the ones induced by Galanin. Since anhedonia is a ... -
Effects of galanin n-terminal fragment (1-15) in sac- charin self-administration and sucrose preference test in rats.
Garcia-Duran, Laura; Cantero-García, Noelia; Flores-Burgess, Antonio
; Gago-Calderon, Belen
; Allén, Francisco; Orio, Laura; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
; Millon-Peñuela, Carmelo
[et al.] (2019-09-12)
The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions in several behavioral tests, and these effects were significantly stronger than the ones induced by Galanin (1-29). Since, ... -
Effects of Galanin N-Terminal fragment (1-15) in the anhedonic behavioural tests in rats.
Garcia-Cantero, Noelia; Flores-Burgess, Antonio; Gago-Calderon, Belen
; Garcia-Duran, Laura
; Alén, Francisco; Orio, Laura; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
; Millon-Peñuela, Carmelo
[et al.] (2021-01-22)
The Galanin N-terminal fragment (1-15)[GAL(1-15)] induces depressant- and anxiogenic-like actions in behavioural tests in rats. Since anhedonia is a core feature of depression, we have analyzed GAL(1-15) actions in ... -
Galanin (1-15) and escitalopram combination in rats reduces alcohol consumption in the ethanol self-administration test and improves escitalopram effects in the forced swimming test.
Cantero García, Noelia; Flores-Burgess, Antonio; Ladrón de Guevara-Miranda, David; Serrano, Antonia; Garcia-Duran, Laura
; Puigcerver-Martinez, Araceli
; Fuxe, Kjell; Narváez, José Ángel
; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
; Millon-Peñuela, Carmelo
[et al.] (2022-07-12)
Recently, we described that Galanin(1-15)[GAL(1-15)] enhanced Escitalopram(ESC) effectiveness in depression symptoms. Moreover GAL(1-15) induces a substantial reduction in alcohol consumption. To investigate the effect of ... -
Galanin (1-15) enhancement of the behavioral effects of a 5-HT1AR agonist and fluoxetine in the forced swimming test gives a new therapeutic strategy against depression: possible role of GALR1-GALR2-5-HT1AR heteroreceptor complexes
Flores-Burgess, Antonio; Millon-Peñuela, Carmelo
; Puigcerver-Martinez, Araceli
; Gago-Calderon, Belen
; Garcia-Duran, Laura
; Cantero-García, Noelia; Narváez, José Ángel
; Santin-Nuñez, Luis Javier
; Fuxe, Kjell; Díaz-Cabiale, Zaida
[et al.] (2019-06-17)
Major Depression is the most frequent mood disorder, with a lifetime prevalence that has been reported to range from 7% to 21%. It is associated with a substantial functional impairment, diminished quality of life, increased ... -
Galanin (1-15) enhances the behavioural effects of escitalopram in the forced swimming test in rats
Garcia-Duran, Laura; Cantero-García, Noelia; Flores-Burgess, Antonio
; Gago-Calderon, Belen
; Puigcerver-Martinez, Araceli
; Narváez, José Ángel
; Santin-Nuñez, Luis Javier
; Millon-Peñuela, Carmelo
; Díaz-Cabiale, Zaida
[et al.] (2021-01-22)
The selective serotonergic reuptake inhibitors (SSRIs) are the most commonly used for the treatment of major depression. Recently, we observed that the Galanin N-terminal fragment (1-15) [GAL(1-15)] enhances the ... -
Galanin (1-15) potentiates the antidepres-sant-like effects induced by Escitalopram in a rat model of depression
Garcia-Duran, Laura; Flores-Burgess, Antonio
; Cantero-García, Noelia; Puigcerver-Martinez, Araceli
; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Millon-Peñuela, Carmelo
; Díaz-Cabiale, Zaida
[et al.] (2021-10-07)
Selective 5-HT reuptake inhibitor antidepressants (SSRIs) are the first choice in major depressive disorder (MDD), but 50% of affected patients do not show improvement. Galanin(1-15) [GAL(1-15)] enhanced Fluoxetine ... -
Galanin n-terminal fragment (1-15) decreases the voluntary alcohol intake in rats
Millon-Peñuela, Carmelo; Flores-Burgess, Antonio
; Castilla-Ortega, Maria Estela
; Gago-Calderon, Belen
; Serrano, Antonia; Sturla, Antonella; Garcia-Duran, Laura
; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
[et al.] (2018-06-28)
Galanin (GAL) is involved in drug abuse and addiction including alcohol intake. In this work, we have analysed the role of the N-terminal GAL fragment (1-15) [GAL(1-15)] in voluntary ethanol consumption in rats using the ... -
Galanin(1-15) enhanced the antidepressant-like effects of escitalopram in the olfactory bulbectomy rats in the forced swimming test through 5-HT1A receptors
Garcia-Duran, Laura; Flores-Burgess, Antonio
; Cantero-García, Noelia; Puigcerver-Martinez, Araceli
; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Millon-Peñuela, Carmelo
; Díaz-Cabiale, Zaida
[et al.] (2022-07-12)
We previously described that Galanin (1-15) [GAL(1-15)] enhances the antidepressant-like effects induced by the SSRI Fluoxetine in the forced swimming test (FST) in naïve rats. In this work, we have analyzed in olfactory ... -
Galanin(1-15) reverses the impaired long-term memory effect of fluoxetine in the novel object recognition test. Role of 5-HT1A receptor in medial prefrontal cortex
Flores-Burgess, Antonio; Millon-Peñuela, Carmelo
; Gago-Calderon, Belen
; Garcia-Duran, Laura
; Cantero-García, Noelia; Coveñas, Rafael; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
[et al.] (2019-12-16)
In this work, we have studied the effects of GAL(1-15) on FLX- mediated effects on the NOR and the OLM, two tasks where FLX treatment impaired long-term memories 24h post-training. Since the mPFC is a core region for the ... -
New augmentation strategy in depression: Galanin (1-15) enhances the behavioral effects of Fluoxetine in the olfactory bulbectomy rat.
Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Millon-Peñuela, Carmelo
; Gago-Calderon, Belen
; Garcia-Duran, Laura
; Cantero-García, Noelia; Puigcerver-Martinez, Araceli
; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
[et al.] (2022-07-12)
Major depression is the largest contributor to global disability by years lived with disability. Selective serotonergic reuptake inhibitors, including fluoxetine (FLX), are the most commonly used antidepressant for the ... -
RawData_Flores-Burgess_2021
Flores-Burgess, Antonio; Millon-Peñuela, Carmelo
; Gago-Calderon, Belen
; Garcia-Duran, Laura
; Cantero-García, Noelia; Puigcerver-Martinez, Araceli
; Narváez, José Ángel
; Fuxe, Kjell; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
[et al.] (Universidad de Málaga, 2022-04-19)
Collection of data published in the article: https://hdl.handle.net/10630/23528 -
The Combination of Galanin (1–15) and Escitalopram in Rats Suggests a New Strategy for Alcohol Use Disorder Comorbidity with Depression
Cantero-García, Noelia; Flores-Burgess, Antonio; Ladrón de Guevara-Miranda, David; Serrano, Antonia; Garcia-Duran, Laura
; Puigcerver-Martinez, Araceli
; Fuxe, Kjell; Narváez, José Ángel
; Santin-Nuñez, Luis Javier
; Díaz-Cabiale, Zaida
; Millon-Peñuela, Carmelo
[et al.] (Universidad de Málaga, 2022-07-25)
Alcohol use disorder (AUD) is highly prevalent, and over 50% of AUD patients also suffer major depressive disorders. Selective 5-HT reuptake inhibitors (SSRIs) can reduce rodent ethanol drinking but exert modest clinical ...