Listar por autor "Aguirre-Gómez, José Ángel"
Mostrando ítems 1-14 de 14
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Efecto neuroprotector de IGF-II en situaciones de estrés neuronal inducido por corticosterona
Aguirre-Gómez, José Ángel
; Martinez-Montañez, Elisa; Pavía-Molina, José; Santín-Núñez, Luis Javier; Estivill-Torrús, Guillermo; García-Fernández, María Inmaculada[et al.] (2013-10-02)
El daño por estrés en tejido neuronal mediado por la presencia de elevados niveles de corticosterona, se relaciona con la producción de alteraciones en funciones cognitivas. Así, el estrés agudo induce un aumento importante ... -
Effects of Nanocrystalline Glass-like Carbon thin films on the SN4741 Dopaminergic cell Parkinson model
Rodriguez-Losada; Romero, Pablo; Estivill-Torrús, Guillermo; Guzmán de Villoria, Roberto; Aguirre-Gómez, José Ángel (2017-10-04)
The interest in carbon nanomaterials has grown within the last decade in view of a wide variety of applications. In this work we test the biocompatibility of a particular nanometer-thin nanocrystalline glass-like carbon ... -
Graphene derivative scaffolds facilitate in vitro cell survival and maturation of dopaminergic SN4741 cells
Rodríguez-Losada, Noela; Wendelbo, Rune; García-Fernández, María Inmaculada; Pavía-Molina, José; Martinez-Montañez, Elisa; Lara-Muñoz, José Pablo; Arenas, Ernest; Aguirre-Gómez, José Ángel[et al.] (2014-11-26)
The emerging carbon nanomaterial Graphene (G), in the form of scaffold structure, has an efficient bioconjugation with common biomolecules and activates cell differentiation of neuronal stem cells, providing a promising ... -
Graphene derivatives as scaffold for ex vivo survival and maturation of dopaminergic SN4741 cells.
Rodríguez-Losada, Noela; Wendelbo, Rune; García-Fernández, María Inmaculada; Pavía-Molina, José; Martín-Montañez, Elisa; Lara-Muñoz, José Pablo; Arenas, Ernest; Aguirre-Gómez, José Ángel[et al.] (2014-09-01)
Carbon nanomaterial Graphene (G) can form a three-dimensional porous structure with efficient bioconjugation and cell differentiation properties, providing a promising scaffold for neural regeneration. Aims: To study this ... -
Graphene oxide and reduced derivates, as powder or film scaffolds, differentially promote dopaminergic neuron differentiation and survival.
Rodríguez-Losada, Noela; Wendelbo, Rune; Ocaña, C; Díaz-Casares, Amelia; Guzmán de Villoria, Roberto; Aguirre-Gómez, José Ángel; Arráez-Sánchez, Miguel Ángel; González-Alegre, P; Medina, MA; Arenas, Ernest; Narváez-Bueno, José Ángel[et al.] (Frontiers, 2020)
Emerging scaffold structures made of carbon nanomaterials, such as graphene oxide (GO) have shown efficient bioconjugation with common biomolecules. Previous studies described that GO promotes the differentiation of neural ... -
The graphene oxide species induce a different biological response in SN4741 Parkinson cell line
Rodríguez-Losada, Noela; Wendelbo, Rune; Aguirre-Gómez, José Ángel; Ocaña Farfán, María del Carmen; Arráez-Sánchez, Miguel Ángel; Díaz-Casares, Amelia; Medina-Torres, Miguel Ángel; Martínez-Moreno, José Manuel; Arenas, Ernest; Narváez-Bueno, José Ángel[et al.] (2019-09-30)
Introduction: Graphene Oxide (GO)has recently emerged as a reliable material to create scaffolds for the neural tissue because of its biocompatibility, electroconductive and physicochemical properties. Graphene is a ... -
Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex
Garcia Diaz, Beatriz; Riquelme, Raquel; Varela Nieto, Isabel; Jiménez-Lara, Antonio Jesús; De-Diego-Barbado, Isabel; Gómez-Conde, Ana Isabel; Matas-Rico, Elisa; Aguirre-Gómez, José Ángel; Chun, Jerold; Pedraza-Benítez, María del Carmen; Santín-Núñez, Luis Javier; Fernández Fernández, Óscar; Rodriguez-de-Fonseca, Fernando; Estivill-Torrús, Guillermo[et al.] (Springer Link, 2014)
Lysophosphatidic acid (LPA) is an intercellular signaling lipid that regulates multiple cellular functions, acting through specific G-protein coupled receptors (LPA1–6). Our previous studies using viable Malaga variant ... -
Nanocrystalline glass-like carbon thin films may be an useful tool in nerve cells regeneration
Rodríguez-Losada, Noela; Romero, Pablo; Guzmán de Villoria, Roberto; Aguirre-Gómez, José Ángel (2017-03-10)
The interest in carbon nanomaterials with high transparency and electrical conductivity has grown within the last decade in view of a wide variety of applications, including biocompatible sensors, diagnostic devices and ... -
Positive biocompatibility of nanocrystalline glass-like carbon thin films
Rodríguez-Losada, Noela; Romero, Pablo; Guzmán de Villoria, Roberto; Aguirre-Gómez, José Ángel (2016-09-27)
The interest in carbon nanomaterials with high transparency and electrical conductivity has grown within the last decade in view of a wide variety of applications, including biocompatible sensors, diagnostic devices and ... -
Positive biocompatibility of several graphene derivatives with dopaminergic cells at long term culture
Rodríguez-Losada, Noela; Wendelbo, Rune; Arenas, Ernest; Aguirre-Gómez, José Ángel (2015-10-28)
The emerging carbon nanomaterial graphene (G) and its oxidized derivative graphene oxide (GO) have recently gained considerable attention in biomedical applications such as cancer therapy or biosensors. It has for example ... -
Positive biocompatibility of several graphene derivatives with dopaminergic cells at long term culture
Rodríguez-Losada, Noela; Wendelbo, Rune; Arenas, Ernest; Aguirre-Gómez, José Ángel (2015-09-23)
Carbon nanomaterial graphene (G) can form a three-dimensional porous structure with efficient bioconjugation and cell differentiation properties, providing a promising scaffold for neural regeneration. Aims: To study this ... -
The novel cyclooxygenase-2 inhibitor GW637185X protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
Aguirre-Gómez, José Ángel; Leo, Giuseppina; Cueto-Galán, Raquel; Andbjer, Beth; Naylor, Alan; Medhurst, Andrew D; Agnati, Luigi F; Fuxe, Kjell[et al.] (Lippincott, Williams & Wilkins, 2008)
En este articulo se estudió el posible papel neuroprotector de un inhibidor novedoso y altamente selectivo de la ciclooxigenasa-2, GW637185X, en un modelo de lesión aguda inducida por 1-metil-4-fenil-1,2,3,6-tetrahidropiridina ...