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Listar por autor "González-Doménech, Carmen María"
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A narrative review about autism spectrum disorders and exclusion of gluten and casein from the diet
González-Domenech, Pablo José; Diaz-Atienza, Francisco; Gutiérrez-Rojas, Luis; Fernández-Soto, María Luisa; González-Doménech, Carmen María (MDPI, 2022-05)Objective: Autism spectrum disorders (ASDs) appear in the early stages of neurodevelopment, and they remain constant throughout life. Currently, due to limitations in ASDs treatment, alternative approaches, such as nutritional ... -
A pandemic within other pandemics. When a multiple infection of a host occurs: SARS-CoV-2, HIV and mycobacterium tuberculosis
González-Doménech, Carmen María; Pérez Hernández, Isabel Ascensión; Gómez Ayerbe, Cristina; Viciana-Ramos, María Isabel; Palacios-Muñoz, María Rosario; Santos-González, Jesús Leandro[et al.] (2021-05-17)By the middle of 2021, we are still immersed in the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The concurrence of this new pandemic in regions ... -
A phenotypic study of the resistome in a peri-urban ecosystem.
González Román, Ana Carmen; Dib, Amira Leila; González-Doménech, Carmen María; García Valdés, Luz María; López Guarnido, Olga; Espigares Rodríguez, Elena[et al.] (Elsevier, 2023)Since the discovery of antibiotics, the dispersion of resistance genes has increased exponentially, leading to the current state in which it has become increasingly difficult to achieve an effective treatment for infectious ... -
Aspectos farmacológicos de darunavir/cobicistat.
González-Doménech, Carmen María; Palacios-Muñoz, María Rosario; Santos-González, Jesús Leandro (Elsevier, 2016-05)Rezolsta® (darunavir/cobicistat) es el primer inhibidor de la proteasa potenciado en combinación fija con un nuevo potenciador farmacológico. Darunavir es actualmente el inhibidor de la proteasa de uso preferente con un ... -
Blueprint for a minimal photoautotrophic cell: conserved and variable genes in Synechococcus elongatus PCC 7942
Delaye, Luis; González-Doménech, Carmen María; Garcillán-Barcia, María P.; Peretó, Juli; De la Cruz, Fernando; Moya, Andrés[et al.] (BMC, 2011-01-12)Background: Simpler biological systems should be easier to understand and to engineer towards pre-defined goals. One way to achieve biological simplicity is through genome minimization. Here we looked for genomic islands ... -
Clinical, virological and phylogenetic characterization of a multiresistant HIV-1 strain outbreak in naive patients in southern Spain
González-Doménech, Carmen María; Viciana-Ramos, María Isabel; Palacios-Muñoz, María Rosario; Delgado, Marcial; Del Arco, Alfonso; Tellez, Francisco; Jarilla, Francisco; Fernández, Sonsoles; Clavijo-Frutos, Encarnación; Santos-González, Jesús Leandro[et al.] (Oxford Academic, 2016-02)Background: We describe the characteristics of an HIV-1 strain with six viral reverse transcriptase mutations (D67N, T69N/D, V118I, V179D, T215S and K219Q), which we have called the Malaga strain. This strain was detected ... -
Cryptococcal infection in HIV-infected patients with CD4+ T-cell counts under 100/μL diagnosed in a high-income country: a multicentre cohort study.
González-Doménech, Carmen María; Pérez-Jacoiste Asín, M.A.; Bisbal, O.; Iribarren, J.A.; Pérez-Rivilla, A.; Mican, R.; Dronda, F.; Vinuesa-García, D.; Macías, J.; Lumbreras, C.; Moreno, S.; Rubio, R.; Members of the Cohorte de la Red de Investigación en Sida (CoRIS)[et al.] (Elsevier, 2020-10-16)Objectives: The World Health Organization recommends routinely screening HIV-infected patients with CD4+ T-cell counts <100/μL for cryptococcal infection to prevent cryptococcal meningitis (CM), based on studies in Sub-Saharan ... -
Denitrification as an important taxonomic marker within the genus Halomonas.
González-Doménech, Carmen María; Martínez-Checa, Fernando; Béjar, Victoria; Quesada, Emilia (Elsevier, 2010-01-27)We have made a comprehensive study of the denitrifying species of the genus Halomonas, evaluating both the phylogenetic and phenotypic relationships amongst them and other species of Halomonas. The phylogenetic analysis ... -
Detección de variantes del SARS-CoV-2 en aguas residuales de hospitales en Perú, 2022.
Marcos-Carbajal, Pool; Yareta-Yareta, José; Otiniano-Trujillo, Miguel; Galarza-Pérez, Marco; Espinoza-Culupu, Abraham; Ramírez-Melgar, Jorge L.; Chambi-Quispe, Mario; Luque-Chipana, Néstor Alejandro; Gutiérrez Ajalcriña, Rosmery; Sucñe Cruz, Víctor; López Chegne, Segundo Nicolás; Santillán Ruiz, Diana; Segura Chávez, Luis Felipe; Sias Garay, Cinthia Esther; Salazar Granara, Alberto; Tsukayama Cisneros, Pablo; Tapia-Paniagua, Silvana Teresa; González-Doménech, Carmen María[et al.] (Revista Peruana de Medicina Experimental y Salud Pública, 2024-05-14)Objetivo. Identificar la presencia del virus SARS-CoV-2 en aguas residuales de hospitales en Perú. Materiales y métodos. Se recolectaron muestras de agua en los efluentes de nueve hospitales del Perú durante marzo y ... -
Diversidad del VIH-1. Transmisión dinámica y resistencias primarias en los nuevos diagnósticos de VIH-1 en la población de Málaga (HUVV) durante los años 2004-2015.
Sena Corrales, Gabriel (UMA Editorial, 2017-06-06)Las Guías de Práctica Clínica recomiendan la realización de un test genotípico de resistencia en todos los pacientes diagnosticados de infección por el VIH-1. Disponer de la secuencia de la retrotranscriptasa (RT) y de la ... -
Diversity and distribution of Halomonas in Rambla Salada, a hypersaline environment in the southeast of Spain.
Oueriaghli, Nahid; González-Doménech, Carmen María; Martínez-Checa, Fernando; Muyzer, Gerard; Ventosa, Antonio; Quesada, Emilia; Béjar, Victoria[et al.] (Oxford University Press-Wiley, 2014-02-01)We have studied the diversity and distribution of Halomonas populations in the hypersaline habitat Rambla Salada (Murcia, southeastern Spain) by using different molecular techniques. Denaturing gradient gel electrophoresis ... -
Diversity of culturable halophilic archaea isolated from Rambla Salada, Murcia (Spain).
Luque, Rocío; González-Doménech, Carmen María; Llamas, Inmaculada; Quesada, Emilia; Béjar, Victoria (Springer Nature, 2012-01-05)We have studied the diversity of culturable halophilic Archaea at Rambla Salada, Murcia (south-eastern Spain). We made 8 samplings at different places in this habitat during the years 2006 and 2007 and isolated a total of ... -
Efficacy and safety of switching to abacavir/lamivudine (ABC/3TC) plus rilpivirine (RPV) in virologically suppressed HIV-infected patients on HAART.
Palacios-Muñoz, María Rosario; Pérez Hernández, Isabel Ascensión; Martínez, M.A.; Mayorga, María Luisa; González-Doménech, Carmen María; Omar, Mohamed; Olalla, Julián; Romero, Alberto; Romero, J.M.; Pérez Camacho, Inés; Hernández-Quero, José; Santos-González, Jesús Leandro[et al.] (Springer, 2016-02-15)We analysed the efficacy and safety of switching from a regimen based on nonnucleoside reverse transcriptase inhibitors (NNRTI) or integrase inhibitors (INI) to ABC/3TC + RPV in virologically suppressed HIV-infected patients. ... -
Emergence as an outbreak of the HIV-1 CRF19_cpx variant in treatment-naïve patients in southern Spain.
González-Doménech, Carmen María; Viciana-Ramos, María Isabel; Delaye, Luis; Mayorga, María Luisa; Palacios-Muñoz, María Rosario; de la Torre, Javier; Jarilla, Francisco; Castaño, Manuel; del Arco, Alfonso; Clavijo-Frutos, Encarnación; Santos-González, Jesús Leandro[et al.] (PLOS Medicine Collection, 2018-01-08)Background: CRF19_cpx is a complex circulating recombination form (CRF) of HIV-1. We describe the characteristics of an outbreak of the CRF19_cpx variant among treatment-naïve patients in southern Spain. Methods: The ... -
Factors associated with the number of drugs in darunavir/cobicistat regimens.
Martinez, Esteban; Negredo, Eugenia; Knobel, Hernando; Ocampo, Antonio; Sanz, José; Garcia-Fraile, Lucio; Martin-Carbonero, Luz; Lozano, Fernando; González-Doménech, Carmen María; Gutierrez, Mar; Montero, Marta; Boix, Vicente; Payeras, Antoni; Torralba, Miguel; González-Cordón, Ana; Alejos, Belén; Pérez-Elías, María Jesús[et al.] (Oxford University Press, 2019-10-05)Background: Darunavir/cobicistat can be used as mono, dual, triple or more than triple therapy. Objectives: To assess factors associated with the number of drugs in darunavir/cobicistat regimens. Methods: A nationwide ... -
Halomonas cerina sp. nov., a moderately halophilic, denitrifying, exopolysaccharide-producing bacterium
González-Doménech, Carmen María; Martínez-Checa, Fernando; Quesada, Emilia; Béjar, Victoria (Microbiology Society, 2008-04-01)Three bacterial strains were isolated from different saline soils in Spain. The novel strains were moderately halophilic, exopolysaccharide-producing, Gram-negative, non-motile rods. The strains required NaCl and grew best ... -
Halomonas fontilapidosi sp. nov., a moderately halophilic, denitrifying bacterium
González-Doménech, Carmen María; Martínez-Checa, Fernando; Quesada, Emilia; Béjar, Victoria (Microbiology Society, 2009-06-01)We have made a polyphasic taxonomic study of strain 5CR(T), isolated from Fuente de Piedra, Málaga, southern Spain. The strain is a moderately halophilic, Gram-negative rod, oxidase-positive and motile by a single polar ... -
Halomonas nitroreducens sp. nov., a novel nitrate- and nitrite-reducing species.
González-Doménech, Carmen María; Béjar, Victoria; Martínez-Checa, Fernando; Quesada, Emilia (Microbiology Society, 2008-04-01)We have carried out a polyphasic taxonomic study of strain 11ST, a halophilic, Gram-negative bacterium that is able to respire on nitrate and nitrite in anaerobiosis. Strain 11ST was isolated from a solar saltern in Cahuil, ... -
High Prevalence of Sequences Included in Transmission Clusters Within Newly Diagnosed HIV-1 Patients in Southern Spain (2004-2015)
González-Doménech, Carmen María; Sena Corrales, Gabriel; Viciana-Ramos, María Isabel; Palacios-Muñoz, María Rosario; Mora-Navas, Laura; Clavijo-Frutos, Encarnación; Santos-González, Jesús Leandro[et al.] (Mary Ann Liebert, 2020-09-09)The presence of transmission clusters (TCs) and their epidemiological characteristics in a treatment-naive cohort of HIV-1 patients in southern Spain over a decade (2004-2015) were evaluated. Protease and reverse transcriptase ... -
Identification of Xenologs and Their Characteristic Low Expression Levels in the Cyanobacterium Synechococcus elongatus.
Álvarez-Canales, Gilberto; Arellano-Álvarez, Guadalupe; González-Doménech, Carmen María; De la Cruz, Fernando; Moya, Andrés; Delaye, Luis[et al.] (Springer, 2015-06-04)Horizontal gene transfer (HGT) is a central process in prokaryotic evolution. Once a gene is introduced into a genome by HGT, its contribution to the fitness of the recipient cell depends in part on its expression level. ...