Listar por autor "González-Muñoz, María Elena"
Mostrando ítems 1-11 de 11
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Analysis of Menstrual Blood Stromal Cells Reveals SOX15 Triggers Oocyte-Based Human Cell Reprogramming
López-Caraballo, Lidia; Martorell-Marugán, Jordi; Carmona-Sáez, Pedro; González-Muñoz, María Elena
(CellPress, 2020)
Cell reprogramming has revolutionized cell and regenerative biology field. However, human iPS derivation remains inefficient and variable. A better knowledge of molecular processes and the rationale underlying the importance ... -
Comparative analysis of single-cell transcriptomics in human and zebrafish oocytes
Can, Handan; Chanumolu, Sree K.; González-Muñoz, María Elena; Prukudom, Sukumal; Otu, Hasan H.; Cibelli, Jose B[et al.] (Springer Nature, 2020-07-08)
Background: Zebrafish is a popular model organism, which is widely used in developmental biology research. Despite its general use, the direct comparison of the zebrafish and human oocyte transcriptomes has not been ... -
Efficient and scalable gene delivery method with easily generated cationic carbon dots.
Algarra-González, Manuel; González-Muñoz, María Elena (BMC, 2024-03-08)
Gene delivery is a complex process with several challenges when attempting to incorporate genetic material efficiently and safely into target cells. Some of the key challenges include not only efficient cellular uptake and ... -
iPS-Derived Early Oligodendrocyte Progenitor Cells from SPMS Patients Reveal Deficient In Vitro Cell Migration Stimulation.
López-Caraballo, Lidia; Martorell-Marugán, Jordi; Carmona-Sáez, Pedro; González-Muñoz, María Elena (MDPI, 2020-07-29)
The most challenging aspect of secondary progressive multiple sclerosis (SPMS) is the lack of efficient regenerative response for remyelination, which is carried out by the endogenous population of adult oligoprogenitor ... -
Modeling chronic cervical spinal cord injury in aged rats for cell therapy studies.
Martín-López, Maria; González-Muñoz, María Elena; Gómez González, Emilio; Sánchez Pernaute, Rosario; Márquez-Rivas, Javier; Fernández-Muñoz, Beatriz[et al.] (Elsevier, 2021-09-30)
With an expanding elderly population, an increasing number of older adults will experience spinal cord injury (SCI) and might be candidates for cell-based therapies, yet there is a paucity of research in this age group. ... -
Monitoring oocyte-based human pluripotency acquisition using synchrotron-based FTIR microspectroscopy reveals specific biomolecular trajectories
Dučić, Tanja; Sánchez-Mata, Alicia; Castillo-Sánchez, Jesús; Algarra-González, Manuel; González-Muñoz, María Elena (Elsevier, 2023)
The reprogramming of human somatic cells to induced pluripotent cells (iPSCs) has become a milestone and a paradigm shift in the field of regenerative medicine and human disease modeling including drug testing and genome ... -
Multifunctionalized Carbon Dots as an Active Nanocarrier for Drug Delivery to the Glioblastoma Cell Line
Algarra-González, Manuel; Soto-Martín, Juan; Pino-González, María Soledad; González-Muñoz, María Elena; Dučić, Tanja (ACS, 2024-03-13)
Nanoparticle-based nanocarriers represent a viable alternative to conventional direct administration in cancer cells. This advanced approach employs the use of nanotechnology to transport therapeutic agents directly to ... -
Oligodendrocyte-specific expression of PSG8-AS1 suggests a role in myelination with prognostic value in oligodendroglioma
Becerra-Rodríguez, María de los Ángeles; González-Muñoz, María Elena; Moore, Tom (Elsevier, 2024-06-10)
The segmentally duplicated Pregnancy-specific glycoprotein (PSG) locus on chromosome 19q13 may be one of the most rapidly evolving in the human genome. It comprises ten coding genes (PSG1-9, 11) and one predominantly ... -
Retrieval of germinal zone neural stem cells from the cerebrospinal fluid of premature infants with intraventricular hemorrhage
Fernández-Muñoz, Beatriz; Rosell-Valle, Cristina; Ferrari, Daniela; Alba-Amador, Julia; Montiel, Miguel Ángel; Campos-Cuerva, Rafael; López-Navas, Luis; Muñoz-Escalona, María; Martín-López, María; Profico, Daniela Celeste; Blanco, Manuel Francisco; Giorgetti, Alessandra; González-Muñoz, María Elena; Márquez-Rivas, Javier; Sánchez Pernaute, Rosario[et al.] (Oxford University Press, 2020-05-30)
Intraventricular hemorrhage is a common cause of morbidity and mortality in premature infants. The rupture of the germinal zone into the ventricles entails loss of neural stem cells and disturbs the normal cytoarchitecture ... -
Synchrotron radiation FTIR microspectroscopy enables measuring dynamic cell identity patterning during human 3D differentiation.
Dučić, Tanja; Rodríguez-Yáñez, Francisco; González-Muñoz, María Elena (Frontiers, 2025-05-21)
Human cell fate specification, particularly in neural development, is difficult to study due to limited access to embryonic tissues and differences from animal models. Human induced pluripotent stem cells (hiPSCs) and ... -
Understanding menstrual blood-derived stromal/stem cells: Definition and properties. Are we rushing into their therapeutic applications?
Sánchez-Mata, Alicia; González-Muñoz, María Elena (CellPress, 2021-12-17)
Cells with mesenchymal stem cell properties have been identified in menstrual blood and termed menstrual blood-derived stem/stromal cells (MenSCs). MenSCs have been proposed as ideal candidates for cell-based therapy in ...